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Reported evidence suggested that high abundance of intrinsic disorder in eukaryotic genomes in comparison to bacteria and archaea may reflect the greater need for disorder-associated signaling and tra...
Transcription factors in the development of Th9 cells
T cells Transcription factors Cytokines
2015/5/21
Cytokines are extracellular proteins that mediate communication between cells. T helper cell subsets secrete specific cytokines that promote the development of inflammation. Naïve CD4+ T cells ac...
A new framework for identifying combinatorial regulation of transcription factors: a case study of the yeast cell cycle
framework identifying combinatorial regulation transcription factors yeast cell cycle
2010/11/15
By integrating heterogeneous functional genomic datasets, we have developed a new framework for detecting combinatorial control of gene expression, which includes estimating transcription factor activ...