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Interplay between chaperones and protein disorder promotes the evolution of protein networks
Interplay between chaperones protein disorder promotes evolution protein networks
2015/12/11
Evolution is driven by mutations, which lead to new protein functions but come at a cost to protein stability. Non-conservative substitutions are of interest in this regard because they may most profo...
Interplay between mutational pathway and spatial drug distribution controls time to evolution of drug resistance
Interplay mutational pathway spatial drug distribution controls time evolution of drug resistance
2012/2/28
Spatial gradients of drug concentration are believed to play an important role in the evolution of drug resistance. We use a stochastic model to show that in a growing population of malignant cells th...
The interplay of microscopic and mesoscopic structure in complex networks
microscopic mesoscopic structure
2011/1/6
Not all nodes in a network are created equal. Differences and similarities exist at both individual node and group levels. Disentangling single node from group properties is crucial for network modeli...
National Science Foundation Funding to Advance Research on Interplay Between Biology and Society(图)
biology ecology genetics
2007/7/5