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南京农业大学农学院《Plant Physiology》发表华健教授课题组“CHROMATIN REMODELING 11-dependent nucleosome occupancy affects disease resistance in rice”（图）
华健 基因转录 蛋白修饰
2023/10/28
染色质重塑主要包括围绕核小体的组蛋白修饰和染色质重塑蛋白介导的染色质构型调控。染色质重塑介导的基因转录表达调控是植物基因转录调控最重要的调控机制之一。然而，目前对于病原菌侵染诱导的寄主植物核小体动态变化及其与基因转录表达的关系尚不清楚。
Pac-Man-like CRISPR enzymes have potential for disease diagnostics
Pac-Man-like CRISPR enzymes disease diagnostics
2017/7/20
University of California, Berkeley, researchers have described 10 new CRISPR enzymes that, once activated, behave like Pac-Man to chew up RNA in a way that could be used as sensitive detectors of infe...
2017 “健康和疾病翻译机”高登研究研讨会（The Gordon Research Seminar on Translation Machinery in Health and Disease）
Health Disease
2017/3/8
The Gordon Research Seminar on Translation Machinery in Health and Disease is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education t...
The role of gluten consumption at an early age in celiac disease development: a further analysis of the prospective PreventCD cohort study
celiac disease children gluten HLA European cohort
2018/11/13
Background: We previously found that the introduction of small quantities of gluten at 4–6 mo of age did not reduce the risk of celiac disease (CD) in a group of high-risk children. However, the consu...
2017应激蛋白在生长，发育和疾病戈登学术会议（The 2017 Gordon Research Conference on Stress Proteins in Growth, Development & Disease）
Stress Proteins Growth Development Disease
2017/1/18
The cellular proteome is constantly exposed to a wide variety of proteotoxic stress conditions. These include external stresses, such as elevated temperatures and radiation damage as well as physiolog...
Get a clue:Biochemist studies fruit fly to understand Parkinson's disease,muscle wasting
Biochemist fruit fly Parkinson's disease muscle wasting
2016/7/4
The fruit fly may help us be less clueless about human muscle development and Parkinson's disease.Erika Geisbrecht, Kansas State University associate professor of biochemistry and molecular biophysics...
The Parkin-like ubiquitin E3 ligase Ariadne-1 in the mammalian brain: Potential implications for neurodegenerative disease
Parkinson's disease movement disorders dopaminergic neurons gene encoding protein ubiquitin proteasome system enzyme E3 ubiquitin ligase
2014/12/10
Parkinson’s disease (PD) is a movement disorder characterized by a massive loss of dopaminergic neurons of nigrostriatal origins. Several genes associated with familial cases of PD encode proteins tha...
NOVEL STRATEGIES TO MODULATE SYNAPTIC COMMUNICATION AND INVESTIGATE THE ROLE OF HDAC6 IN ALZHEIMER’S DISEASE
Photochemistry GABA_A receptors Alzheimer's disease Tau HDAC6
2014/12/10
Neuronal communication is mediated by chemical signaling at the synapse. The underlying molecular mechanisms of learning and memory are poorly understood. Very few tools are available to study how mem...
Regulation of outer surface lipoprotein A in the Lyme disease spirochete Borrelia burgdorferi
Borrelia burgdorferi OspA
2015/5/21
Borrelia burgdorferi, a bacterium which causes Lyme disease, is maintained in nature through a cycle involving two distinct hosts: a tick vector and a mammalian host. To adapt to these two diverse env...
专著信息
书名
A new strategy to combat Alzheimer’s disease. Combining radical-scavenging potential with metal-protein-attenuating ability in one molecule
语种
英文
撰写或编译
作者
Hong-Fang Ji,Hong-Yu Zhang
第一作者单位
出版社...