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Protein Transduction Domain Mimics by ROMP and Their Bioactive Cargo Delivery
Pure sciences Gene delivery Protein delivery Protein transduction domains Romp Synthetic transporters Transfection
2014/11/21
Currently, most of the commercially available therapeutics are all targeting cell surface receptors which constitutes only a small portion of the targets found in the cells. Therefore, reaching intrac...
Guanidinium-Rich ROMP Polymers Drive Phase, Charge, and Curvature-Specific Interactions with Phospholipid Membranes
Protein Transduction Domains Cell-Penetrating Peptides Membranes Phospholipids Vesicles Drug Delivery
2014/11/21
Protein transduction domains (PTDs) and their and their synthetic mimics are short sequences capable of unusually high uptake in cells. Several varieties of these molecules, including the arginine-ric...