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Cyclooxygenase Inhibition Limits Blood-Brain Barrier Disruption following Intracerebral Injection of Tumor Necrosis Factor-alpha in the Rat
cyclooxygenase-2 COX-2 COX-1 prostaglandin E2 neuroinflammation blood-brain barrier ischemia stroke matrix metalloproteinase MMP-3 MMP-9 gelatinase B stromelysin-1 oxidative stress indomethacin cyclooxygenase-1 glutathione free radicals MRI
2015/7/29
Increased permeability of the blood-brain barrier (BBB) is important in neurological disorders. Neuroinflammation is associated with increased BBB breakdown and brain injury. Tumor necrosis factor-alp...
Probiotic supplementation affects markers of intestinal barrier,oxidation,and inflammation in trained men;a randomized,double-blinded,placebo-controlled trial
Probiotics Leaky gut Intense exercise Oxidative stress and inflammation
2015/7/24
Probiotics are an upcoming group of nutraceuticals claiming positive effects on athlete’s gut health, redox biology and immunity but there is lack of evidence to support these statements.We conducted ...
Barrier disruption in STAT6VT transgenic mice as a potential model for atopic dermatitis skin inflammation
STAT6VT transgenic Atopic Dermatitis
2015/5/25
Atopic dermatitis (AD) is a pruritic, chronic inflammatory skin disease with a lifetime prevalence of 10-20% in children and 1-3% in adults, worldwide. In the past three decades, prevalence of the dis...
Brain tumours: Successes and challenges on the other side of the blood-brain barrier
Brain tumours the blood-brain barrier cancers
2015/4/21
Tumours of the central nervous system encompass a large variety of cancers, ranging from slow-growing to rapidly progressive. Although comparatively rare in adults, central nervous system malignancies...
Efficacy of hyaluronic acid - carboxymethyl cellulose membrane (Seprafilm®) and polylactic acid barrier film (Surgiwrap™) for the prevention of adhesions after thyroid surgery: an experimental model
Anti-adhesive barriers thyroidectomy adhesion
2011/3/22
Adhesions occurring after initial surgery increase complications in secondary thyroid operations. Therefore use of anti-adhesive barriers may reduce complication rates of secondary thyroid operations....
Clinical comparison of Bio-Oss plus 10% collagen with a bioabsorbable collagen barrier or coronally advanced flap in treatment of mandibular molars class II furcation defects
Guided tissue regeneration Furcation defect Membranes Collagen Coronally advanced flap
2009/12/7
Background and Aim: Furcation defects are one of the most challenging problems in periodontal therapy. Regenerative treatment significantly improves the prognosis of the involved teeth. The aim of thi...
Choice of Female-Controlled Barrier Methods Among Young Women and Their Male Sexual Partners
Female-Controlled Barrier Young Women Male Sexual Partners
2009/9/16
Little is known about the factors associated with the choice of female-controlled, over-the-counter barrier contraceptive methods among women and their male sexual partners.
Methods: Predictors of...
Breaching the Blood-Brain Barrier as a Gate to Psychiatric Disorder
Blood-Brain Barrier Psychiatric Disorder
2009/9/3
The mechanisms underlying the development and progression of psychiatric illnesses are only partially known. Clinical data suggest blood-brain barrier (BBB) breakdown and inflammation are involved in ...
Blood-brain and blood-lung barrier alteration by dysbaric exposure
decompression blood-lung exposure
2009/7/20
Failure of certain circulating substances to penetrate specific organs led to the concept of blood-organ barriers. Such barriers can be altered by various physical or chemical means. This report conce...
Increased blood-brain barrier permeability to tetracycline in rabbits under dysbaric conditions
decompression tetracycline permeability rabbits
2009/7/17
Alteration of the blood-brain barrier (BBB) by dysbaric exposure may have relevance in several areas of hyperbaric medicine. Drugs administered to persons exposed to dysbaric conditions, e.g., divers,...
Changes in blood-brain barrier permeability to drugs in decompressed rats
decompression human blood brain barrier animal rat drug
2009/7/16
A study has been made of changes in permeability of the blood-brain barrier (BBB) to drugs following exposure to compression-decompression. Fifty-five rats were exposed to 6.1 b (abs) air for 90 min a...
Microbubble damage to the blood-brain barrier: relevance to decompression sickness
decompression pulmonary blood brain barrier bubbles animal Guinea Pigs
2009/7/8
Decompression sickness affecting the nervous system is still a serious problem in diving, but the mechanisms involved are in dispute. Although microbubbles can be detected in the pulmonary artery on d...
The Effects of Vitamin E on Gastric Ulcers and Gastric Mucosal Barrier in Stress Induced Rats
Vitamin E Stress Gastric mucosal barrier
2009/7/6
Effects of vitamin E on gastric ulcers gastric mucosal barrier were in-vestigated in cold + restraint stress (CRS) induced rats. In this study 21 males two month old Swiss Albino Rats were used. Stres...
The Protective Effect of Vitamins E and C on The Gastric Mucosal Barrier in Rats Irradiated With X-Rays
X-rays Gastric mucosal barrier Vitamin E Vitamin C
2009/7/1
The protective effect of vitamins E and C on the gastric mucosal barrier in rats irradiated with X-rays was investigated. Thirty-two male Wistar Albino rats were used. The animals were divided into fo...
The Effects of Allopurinol on Stomach Mucosal Barrier of Rats Subjected to Ischemia-Reperfusion
Ischemia and reperfusion stomach mucosal barrier allopurinol
2009/6/30
The present experimental study was carried out on rats subjected to ischemia and reperfusion. The effects of allopurinol on mucus, an important component of the stomach mucosal barrier, were investiga...