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One of the major advances in preventing malformations in the past few decades had its origin in the observation by Smithells et al (1) that multivitamin preparations are protective against neural t...
Background: Apolipoprotein E (APOE), which its ε4 allele has been reported as a risk factor in late onset Alzheimer’s disease (AD), is the main cholesterol carrier in the brain. ATP-binding cassette t...
cMethods: One hundred and ninety-six patients with brucellosis and 81 healthy farmers (controls) who owned infected animals and consumed their contaminated dairy products were included in this study. ...
Background: Heme oxygenase 2 (HMOX2) is an important antioxidative stress enzyme found in the endothelial cells of blood vessels and adventitial nerves. This enzyme in collaboration with heme oxygenas...
To investigate the association between the 3 most frequently observed single nucleotide polymorphisms of the NAT2 gene and the risk of developing prostate cancer in the Turkish population. Materials a...
Background: In the visceral leishmaniasis (VL), parasites reside in reticuluendothelial system, mainly in macrophages. Endothelial Selectin (E-selectin) might play an important role in leukocyte-endot...
The phamacogenetics is being used to predict whether the selected chemotherapy will be really effective and tolerable to the patient. Irinotecan, oxidized by CYP3A4 to produce inactive compounds, is u...
Ameloblastin is one of the extracellular matrix proteins in tooth enamel and may be responsible for autosomal amelogenesis imperfecta (AI), since it plays a significant role in enamel crystal growth. ...
Background: The genetic variance determining plasma lipid and lipoprotein concentrations may modify individual responsiveness to alterations in dietary fat and cholesterol content. Objective: The a...

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