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Chagas disease caused by the protozoan Trypanosoma cruzi is the leading cause of heart disease in Latin America. After an acute phase that typically includes few symptoms, a chronic cardiac phase occu...
Background. Trypanosoma cruzi infection is induced by triatomine contaminated feces containing metacyclic trypomastigotes acquired via small wounds in the skin. Natural unspecific and adaptive humoral...
Cellular peptidase profiles from non-infected and Trypanosoma cruzi-infected hepatocyte cell cultures were characterized by substrate-SDS-PAGE containing different copolymerized proteins. A 100-kDa ...
Nineteen stocks of Trypanosoma cruzi originating from several endemic countries for Chagas‘ disease in Central and South America were subjected to two-dimensional protein electrophoresis analysis. The...
An in vitro infection system of Trypanosoma cruzi and HeLa cells was used to measure the anti-T. cruzi activities of various calcium antagonists classified into dihydropyridines, diphenylalkylamines, ...

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