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Down regulation of miR-203 in radiation- induced thymic lymphoma promoted cells proliferation and inhibited apoptosis
TANK-binding kinase 1 (TBK1) SLUG (SNAI2) Cyclin D1 (CCND1)
2015/11/24
To investigate the role of miR-203 in radiation-induced thymic lymphoma (RITL).Methods A 60Co irradiator was used for total-body irradiation. MicroRNAs(miRNAs) level was assayed by qRT-PCR. Cell proli...
Cytotoxic Activity and Apoptosis Induction of Hypericum scabrum L.
Traditional Medicine Caspase-3 Apoptosis Annexin V Protein
2015/11/9
Background: One of the acquired biological hallmarks of tumor multistep development is the resistance of cancer cells to apoptosis; therefore, induction of apoptosis is an important therapeutic approa...
THE PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR γ ANTAGONIST, GW9662, ALTERS UVB-INDUCED INFLAMMATORY RESPONSES, APOPTOSIS, AND DELAYED HYPERPROLIFERATION
PPARγ UVB COX-2
2015/1/28
It has recently been shown that the gamma subtype of the peroxisome proliferator-activated receptor (PPARγ) is a target of ultraviolet B (290-320 nm; UVB) irradiation, and that PPARγ activation is nec...
Polyamines and Alveolar Macrophage Apoptosis during Pneumocystis Pneumonia
Polyamines Alveolar Macrophage Apoptosis Pneumocystis Pneumonia
2015/1/28
Pneumocystis pneumonia (PCP) is the leading opportunistic disease in immunocompromised individuals, particularly in AIDS patients. The alveolar macrophage (AM) is the major type of cell responsible fo...
THE PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR γ ANTAGONIST, GW9662, ALTERS UVB-INDUCED INFLAMMATORY RESPONSES, APOPTOSIS, AND DELAYED HYPERPROLIFERATION
PPARγ UVB COX-2
2015/1/19
It has recently been shown that the gamma subtype of the peroxisome proliferator-activated receptor (PPARγ) is a target of ultraviolet B (290-320 nm; UVB) irradiation, and that PPARγ activation is nec...
Polyamines and Alveolar Macrophage Apoptosis during Pneumocystis Pneumonia
Polyamines Alveolar Macrophage Apoptosis Pneumocystis Pneumonia
2015/1/19
Pneumocystis pneumonia (PCP) is the leading opportunistic disease in immunocompromised individuals, particularly in AIDS patients. The alveolar macrophage (AM) is the major type of cell responsible fo...
The PI3K/AKT Pathway and FOXO3a Transcription Factor Mediate High Glucose-Induced Apoptosis in Neonatal Rat Ventricular Myocytes
Myocytes Cardiac Apoptosis gleditsioside B
2015/10/12
Background:: PI3K/AKT pathway plays major roles in regulating cardiomyocyte metabolism. The roles of PI3K/AKT pathway and FOXO3a in mediating high glucose-induced apoptosis in cardiomyocytes remain un...
Vernonia amygdalina—Induced Growth Arrest and Apoptosis of Breast Cancer (MCF-7) Cells
Vernonia amygdalina MCF-7 Cells Apoptosis Necrosis Cellometer Imaging
2013/2/19
Breast cancer is the second leading cause of cancer-related deaths of women in the United States. Fortunately, the mortality rate from breast cancer has decreased in recent years due to an increased e...
Reactive oxygen species induced oxidative stress, neuronal apoptosis and alternative death pathways
Apoptosis Caspases Cell Death Mitochondria PCBs Reactive Oxygen Species
2013/1/28
Reactive oxygen species (ROS) are produced as a byproduct of cellular metabolic pathways and function as a critical second messenger in a variety of intracellular signaling pathways. The excessive int...
Assessment of Sperm Apoptosis and Semen Quality in Infertile Men-Meta Analysis
Assessment Sperm Apoptosis Semen Quality Infertile Men-Meta Analysis
2015/9/25
Intrinsic (mitochondrial) pathway and extrinsic pathway which is done by cell receptors.2 Apoptosis has a significant relation with infertility of men.3 The more immature the testicle, the more apopto...
中国医学科学院实验血液学国家重点实验室王建祥课题组在Leukemia期刊上发表"PIG7, transactivated by AML1, promotes apoptosis and differentiation of leukemia cells with AML1-ETO fusion gene"
血液学 国家重点实验室 王建祥 课题组 Leukemia期刊
2012/2/23
中国医学科学院实验血液学国家重点实验室王建祥课题组在在Leukemia期刊发表文章"PIG7, transactivated by AML1, promotes apoptosis and differentiation of leukemia cells with AML1-ETO fusion gene.”
Effects of high-dose major components in oral disinfectants on the cell cycle and apoptosis in primary human gingival fibroblasts in vitro
Cell cycle and apoptosis Human gingival fibroblasts Oral disinfectants
2010/11/26
We evaluated the effects of high-dose major components in oral disinfectants on oral cells from the standpoints of the cell cycle and apoptosis. We examined the viability and cell cycle of human gingi...
Effects of long-term passive smoking on vascular endothelial growth factor and apoptosis markers expression in lens and corneal epithelial cells:An experimental study
Smoking vascular endothelial growth factor apoptosis lens cornea
2010/1/11
Aim: To determine the effects of smoking on vascular endothelial growth factor (VEGF) expression and apoptosis in lens and corneal epithelial cells. Materials and methods: This experimental study incl...
Role of Calcium Signals on Hydrogen Peroxide-Induced Apoptosis in Human Myeloid HL-60 Cells
caspases calcium signal apoptosis mitochondria H2O2 HL-60 cells
2009/10/26
The present study is aimed to determine the role of calcium signaling evoked by the oxygen radical, hydrogen peroxide (H2O2) and the specific inhibitor of calcium reuptake thapsigargin on apoptosis in...
Engineered FADD Induces Apoptosis via an Artificial Death-Inducing Signaling Complex (DISC)
apoptosis FADD biotechnology DISC engineered protein
2009/10/26
An engineered Fas-associated death domain protein (FADD), 2DEDplusE—made previously by fusing the tandem DEDs of FADD to the E protein of lambda phage-greatly enhances apoptosis-inducing activity in a...