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Anxiety,Depression,Coronary Artery Disease and Diabetes Mellitus;an Association Study in Ghaem Hospital,Iran
Coronary Artery Disease Anxiety Depression Angiography
2015/10/14
Background: There is an increasing trend in the prevalence of coronary artery disease (CAD) in Iran.
Haplotype based association study between t-PA gene and essential hypertension
Haplotype based association study t-PA gene essential hypertension
2009/4/20
Several previous studies have shown that essential hypertension (EH) is associated with fibrinolysis. Tissue plasminogen activator (t-PA) plays a key role in fibrinolysis. Thus, it is possible that ...
Association study: the aminopeptidase A gene and essential hypertension
essential hypertension aminopeptidase A single nucleotide polymorphism haplotype genetic association study
2009/4/9
Aminopeptidase A (APA) cleaves the N-terminal aspartyl acid residue of angiotensin II (Ang II) to produce angiotensin III (Ang III). It has been reported that the APA knockout mouse exhibits elevated ...
5个精神分裂症高发家系与COMT关联的分析Association Study of Five Pedigree with High Incidence of Schizophrenia
精神分裂症 关联 儿茶酚氧位甲基转移酶 基因 多态性
2008/1/16
本研究旨在探测儿茶酚氧位甲基转移酶基因（COMT）多态性与精神分裂症（SP）的关系，搜寻中国汉族人精神分裂症易患性基因。 应用聚合酶链反应（PCR）和限制性片段长度多态性（RFLP）方法对5个精神分裂症高发家系进行初步研究。 用改进的传递/不平衡（TDT）进行统计分析，结果表明，在5个精神分裂症高发家系中，COMT基因与精神分裂症相关联（P=0.0455）。 研究结果提示，在我们研究的家系中...
载脂蛋白E基因多态性与2型糖尿病脑梗死的关系Association Study of Apolipoprotein E Gene Polymorphism and Cerebral Infarction in Type 2 Diabetic Patients
载脂蛋白E 基因多态性 2型糖尿病 脑梗死
2008/1/6
摘要研究载脂蛋白E (ApoE) 基因多态性与中国东北汉族2型糖尿病合并脑梗死的关系。采用聚合酶链反应－限制性片段长度多态性（PCR-RFLP）技术，检测了208例个体的ApoE基因多态性，其中对照（CON）组69例，2型糖尿病无大血管病变（T2DM）组67例和2型糖尿病合并脑梗死（T2DMCI）组72例；同时测定了其中70例T2DMCI患者的血脂含量。CON组等位基因频率为：ε2 9.6％、ε3...