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NGAOUNDERE AND YAOUNDE, CAMEROON – When Bobbo Hamadou gets up in the morning, he opens the door and window in his house. This is not just to air out his mattress – but to lower the concentration of ra...
DHA-rich n–3 fatty acid supplementation decreases DNA methylation in blood leukocytes: the OmegAD study
fish oil DHA EPA DNA methylation LINE-1 Alzheimer disease
2018/11/20
Background: Dietary fish oils, rich in long-chain n–3 (ω-3) fatty acids (FAs) [e.g., docosahexaenoic acid (DHA, 22:6n–3) and eicosapentaenoic acid (EPA, 20:5n–3)], modulate inflammatory reactions thro...
Dietary supplementation with eicosapentaenoic acid, but not with other long-chain n−3 or n−6 polyunsaturated fatty acids, decreases natural killer cell activity in healthy subjects aged >55 y
Fish oil immunity natural killer cell
2016/6/12
Animal studies showed that dietary flaxseed oil
[rich in the n3 polyunsaturated fatty acid -linolenic acid
(ALA)], evening primrose oil [rich in the n6 polyunsaturated
fatty acid -linolenic acid (...
Water incorporated into a food but not served with a food decreases energy intake in lean women
Energy density energy intake lean women
2016/6/1
Previous research showed that decreasing the
energy density (kJ/g) of foods by adding water to them can lead
to reductions in energy intake. Few studies have examined how
water consumed as a bevera...
Low-dose folic acid supplementation decreases plasma homocysteine concentrations: a randomized trial
Supplements folic acid folate
2016/5/27
An elevated plasma total homocysteine
concentration is a risk factor for cardiovascular disease and neural
tube defects. A high daily intake of supplemental folic acid is
known to decrease total ho...
A Proper Enteral Nutrition Support Improves Sequential Organ Failure Score and Decreases Length of Stay in Hospital in Burned Patients
Burns Enteral Nutrition Systemic Inflammatory Response Syndrome
2016/1/26
Background: Severe burned patients developed metabolic imbalances and systemic inflammatory response syndrome (SIRS), which can lead to malnutrition, impaired immunologic response, multiple organ fail...
Aged rat heart: Modulation of age-related respiratory defects decreases ischemic-reflow injury
Mitochondria Cytochrome Oxidase Complex III Myocardial Infarction Aging
2013/1/29
Myocardial injury increases in the elderly heart during ischemia and reperfusion. Mitochondria, the key targets and sources of injury during ischemia and reperfusion, sustain ischemic damage to the el...
Caustic esophageal injury decreases the number of interstitial cells of Cajal in the rat esophagus
Caustic esophageal injury interstitial cells of Cajal esophagus
2010/10/14
To evaluate the effect of caustic esophageal injury (CEI) on the number of interstitial cells of Cajal (ICC). Materials and methods: Wistar rats were divided into 3 groups: control, acid, and alkali i...
Hyperbaric oxygenation decreases blood flows in normal and septic rats
HBO hyperbaric septic animal rat
2009/7/8
The purpose of the study reported here was to characterize the effects of acute exposure to 100% oxygen at a pressure of 202.6 kPa on hemodynamics and organ blood flow in antibiotic-controlled bacteri...
Oxygen pre-breathing decreases dysbaric diseases in UW sheep undergoing hyperbaric exposure
disabled submarine bone compartment syndrome bubbles bone ischemia necrosis dysbaric osteonecrosis air oxygen pre-breathing animal sheep
2009/6/2
Prolonged exposure of humans and animals to increased pressure as in a disabled submarine (DISSUB) can saturate the body's tissues with dissolved N2 as compressed air is breathed. Decompression-induce...
Unilateral injection of neuropeptide Y decreases blood flow in the injected testis but may also increase blood flow in the contralateral testis
NPY innervation
2009/2/18
Neuropeptide Y (NPY) receptors have recently been described in intratesticular arterioles, but the role of NPY in testicular blood-flow regulation has not been examined. To explore this, we admin...
Testosterone decreases 3beta-hydroxysteroid dehydrogenase-isomerase messenger ribonucleic acid in cultured mouse Leydig cells by a strain-specific mechanism
Steroidogenesis testis inbred mice androgen
2009/2/17
We previously reported a strain-related difference in basal 3beta-hydroxysteroid dehydrogenase-isomerase (3betaHSD) activity in response to testosterone in cultured Leydig cells. The data suggested ...
Mouse epididymal sperm contain active P450 aromatase which decreases as sperm traverse the epididymis
Spermatozoa estrogen efferent ductules cytoplasmic droplet testicular excurrent ducts
2009/2/16
Recently we reported that mouse germ cells in the testis contain active P450 aromatase (P450arom), the enzyme that converts androgens to estrogens. This finding suggested that germ cells have the ...
Vitamin A supplementation in iodine-deficient African children decreases thyrotropin stimulation of the thyroid and reduces the goiter rate
Vitamin A iodine supplementation deficiency Africa
2008/12/17
Background: Vitamin A (VA) deficiency (VAD) and iodine deficiency (ID) often coexist in children in Africa. VAD may affect thyroid function and the response to iodine prophylaxis.Objective: The aim wa...
Zinc supplementation decreases incidence of infections in the elderly: effect of zinc on generation of cytokines and oxidative stress1,2,3
Elderly subjects infections interleukin 2 mRNA • zinc oxidative stress tumor necrosis factor
2008/12/10
Background: Zinc deficiency, cell-mediated immune dysfunction, susceptibility to infections, and increased oxidative stress have been observed in elderly subjects (ie, those >55 y old). Zinc is an eff...