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Background: Iron deficiency is common in obese subjects. This may be due to an increase in serum hepcidin and a decrease in iron absorption from adiposity-related inflammation.
Phenolic compounds act as food antioxidants. One of the postulated mechanisms of action is chelation of prooxidant metals, such as iron. Although the antioxidative effect is desirable, this mechani...
Iron-fortified school breakfasts have been introduced in Peru to combat childhood iron deficiency.
Ascorbic acid has a pronounced enhancing effect on the absorption of dietary nonheme iron when assessed by feeding single meals to fasting subjects. This contrasts with the negligible effect on iro...
Inositol hexaphosphate (IP6) is a well-known inhibitor of iron absorption, whereas the effects of the less-phosphorylated derivatives of IP6 are less known.
The characteristics of vegetarian diets suggest that these diets would have lower dietary iron bioavailability than nonvegetarian diets, but there is no evidence of iron deficiency in vegetarians.
We aimed to examine the influence of iron status on iron absorption during pregnancy by measuring supplemental iron absorption, red blood cell iron incorporation, and iron status in pregnant women.
Iron is an essential element for all living organisms. It is a key functional component of oxygen transporting and storage molecules and of many enzymes. It is well established that the bioavailabilit...
Background: The use of stable isotopes has provided valuable insights into iron absorption in humans, but the data have been limited to nonheme iron. Objective: Our objectives were to produce heme iro...
Phytic acid in cereal-based and legume-based complementary foods inhibits iron absorption. Low iron absorption from cereal porridges contributes to the high prevalence of iron deficiency in infants fr...
Muscle tissue from various sources is known to promote nonheme-iron absorption. However, systematic studies of the dose dependency of this effect of meat on iron absorption from an inhibitory meal wit...
Vitamin A and β-carotene were recently reported to enhance iron absorption by counteracting the inhibitory effect of phytic acid in cereal-based meals and of polyphenol-containing beverages on nonheme...
Studies conducted in human infants suggest developmental changes in the regulation of iron absorption; however, little is known about the molecular mechanisms regulating iron absorption during infancy...
Adaptation of iron absorption in response to dietary iron bioavailability is less likely in premenopausal women, who generally have lower iron stores, than in men.
One potentially sustainable approach to improving iron status at the community level is to encourage the consumption of local ascorbic acid–rich foods, in conjunction with meals high in nonheme iron.

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