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Open access to novel dual flow chamber technology for in vitro cell mechanotransduction, toxicity and pharamacokinetic studies
cell mechanotransduction toxicity and pharamacokinetic studies
2010/2/25
The novel flow chamber design provides predictable and well defined mechanical forces at the surface of a cell monolayer, showing improvement over previously tested commercial chambers. The predictabi...
The imperative for controlled mechanical stresses in unraveling cellular mechanisms of mechanotransduction
controlled mechanical stresses unraveling cellular mechanisms mechanotransduction
2010/2/26
The results of this study challenge the basic premise of in vitro mechanotransduction studies, i.e. that a controlled flow regime is applied to impart a defined mechanical stimulus to cells. These res...