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STUDY OF CORRELATION BETWEEN SYSTOLIC BLOOD PRESSURE AND ANGIOTENSIN CONVERTING ENZYME (ACE) ACTIVITY IN STZ INDUCED DIABETIC RATS
STZ induced diabetic rats Diabetes mellitus morbidity mortality
2010/1/6
Background: Diabetes mellitus is a worldwide health problem affecting 1-2% of the population. It is responsible for numerous morbidity and mortality consequences due to vascular events such as hyperte...
目的: 观察HBeAg和HBsAg对人肝癌细胞系HepG2细胞中血管紧张素转化酶(ACE)分泌的影响. 方法: 利用本所既往构建的表达乙肝病毒(HBV)表面抗原和E抗原的真核表达载体pcDNA3.1(-)-HBsAg、pcDNA3.1(-)-HBeAg及空载体pcDNA3.1(-)转染HepG2细胞, 观察转染24, 48 h后细胞上清中ACE活性和炎性细胞因子IL-6、IL-8的变化. 培养细胞...
目的:探讨肾素-血管紧张素系统(RAS)和转化生长因子-β1(TGF-β1)在肌营养不良(MD)中的表达及与肌肉纤维化的关系。方法:应用Western印迹分析和三免疫荧光标记检测了杜氏肌营养不良(DMD)、Becker型肌营养不良(BMD)和先天性肌营养不良(CMD)患者肌肉活检标本中血管紧张素转移酶(ACE)、血管紧张素Ⅱ(AngⅡ)1型(AT1)受体和TGF-β1的表达及共同定位。结果:Wes...
A Method of Teaching the Pharmacology of ACE Inhibitors for the Treatment of Hypertension
Method Teaching Pharmacology ACE Treatment Hypertension
2016/3/11
A method of teaching the pharmacology of angiotensin converting enzyme inhibitors (ACE-I) for the treatment of hypertension is reviewed. A multimedia classroom presentation is used in the formal class...