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Sho-seiryu-to Suppresses Histamine Signaling at the Transcriptional Level in TDI-Sensitized Nasal Allergy Model Rats
allergy gene expression histamine H1 receptors histamine signaling histidine decarboxylase Th2 cytokines
2010/11/16
SST significantly suppressed TDI-induced nasal allergy-like symptoms. TDI provocation showed a significant up-regulation of histamine H1 receptor (H1R) and histidine decarboxylase (HDC) gene expressio...
Analysis of Helper T Cell Responses to Cry j 1-Derived Peptides in Patients with Nasal Allergy: Candidate for Peptide-Based Immunotherapy of Japanese Cedar Pollinosis
Cry j 1 immunotherapy nasal allergy peptide Th response
2010/11/16
Our results suggest four Cry j 1-derived peptides (p61-80, p115-132, p206-225 and p337-353) may be considered to be the immunodominant T-cell epitopes of the Cry j 1 molecule, and can be useful for th...