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山东胃癌高低发人群Lewis基因多态性分析Analysis of Lewis Gene Polymorphism in High and Low Incidence Area of Gastric Cancer in Shandong Province
胃癌 高低发人群 Lewis基因多态性
2007/12/30
摘要应用PCR产物直接测序的方法，检测山东省胃癌高发的临朐人群和低发的苍山人群中Lewis基因多态性T59G的分布,旨在探讨山东临朐和苍山地区胃癌发病率显著不同的内在原因，为阐明临朐地区胃癌高发的机制提供实验依据。结果表明,T59G突变个体在临朐和苍山人群中的分布频率分别为34.5%和31.6%，差别无统计学意义，P＞0.05,OR为1.14 （95% CI,0.59~2.19）。提示就此点突变而...
Interferon-Gamma Gene Polymorphism in Iranian Patients with Multiple Sclerosis
Gene Polymorphism Interferon Multiple Sclerosis
2010/2/4
Interferon- gamma (IFN- γ) is an important immune regulator and inflammatory cytokine which is implicated in the pathogenesis of multiple sclerosis (MS). A single nucleotide polymorphism, T to A, at p...