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Preventative Effect of a Flavonoid, Enzymatically Modified Isoquercitrin on Ocular Symptoms of Japanese Cedar Pollinosis
diet therapy flavonoid Japanese cedar pollen pollinosis quercetin
2010/11/16
During the entire study period, ocular symptom + medication score for the EMIQ group was significantly lower (p < 0.05) than that of the placebo group. When limited to the period, ocular symptom score...
Effects of Pranlukast Hydrate on Airway Hyperresponsiveness in Non-Asthmatic Patients with Japanese Cedar Pollinosis
airway responsiveness allergic rhinitis leukotriene one airway-one disease pranlukast hydrate
2010/11/16
Background: Recent studies have suggested that allergic rhinitis is closely related to bronchial asthma, reflecting the "one airway-one disease" hypothesis. It is unclear if the effects of pranlukast,...
Patterns of Drug Prescription for Japanese Cedar Pollinosis Using a Clinical Vignette Questionnaire
allergic rhinitis guideline Japan physician's practice patterns questionnaires
2010/11/17
Our investigation suggested that, compared to ENTs, GPs and IMs have a lower tendency to concomitantly prescribe drugs for localized treatment such as nasal corticosteroids and eye drops with oral med...
Enhanced Production of IgE Anti-Japanese Cedar Pollen Specific Antibodies by Peripheral Blood B Cells from Patients with Japanese Cedar Pollinosis
B cells class switching ELISA immobilized anti-CD3 Japanese cedar pollen
2010/11/17
Background: IgE antibodies against Japanese cedar pollen (JCP) play an important role for the pathogenesis of the cedar pollinosis, but the mechanism of their production has been unclear. We explored ...
Effect of Cry-consensus Peptide, a Novel Recombinant Peptide for Immunotherapy of Japanese Cedar Pollinosis, on an Experimental Allergic Rhinitis Model in B10.S Mice
allergic rhinitis Cry j 1 Cry j 2 Japanese cedar pollinosis T-cell epitope
2010/11/18
Cry-consensus peptide markedly inhibited Cry j 1-induced sneezes, eosinophil infiltration, and eosinophil peroxidase (EPO) activity in nasal tissue. Cry-consensus peptide inhibited the production of a...
Relationship between Airborne Cry j 1 and the Onset Time of the Symptoms of Japanese Cedar Pollinosis Patients
Cry j 1 electron spin resonance (ESR) radical immunoassay Japanese cedar (JC) pollinosis pollen information symptom score
2010/11/18
Background: Some patients with Japanese cedar (JC) pollinosis already show pollinosis symptoms before the first day of the pollen season as determined by microscopic pollen counts.
Methods: Airborne ...
Inhibition of the Antigen Provoked Nasal Reaction by Second-generation Antihistamines in Patients with Japanese Cedar Pollinosis
allergic rhinitis epinastine hydrochloride fexofenadine hydrochloride nasal provocation rhinoscopy
2010/11/19
Background: Epinastine hydrochloride and fexofenadine hydrochloride, the second-generation antihistamines, are largely used in the indication of allergic rhinitis in Japan. The purpose of this study w...
Effect of modified immunotherapy with an allergen-pullulan conjugate in patients with Japanese cedar pollinosis
eosinophil immunotherapy Japanese cedar pollinossis mast cell seasonal allergic rhinitis Th1 cytokine Th2 cytokine
2010/11/25
Immunologic mechanisms of allergen immunotherapy are still incompletely understood. Immunotherapy of a higher maximum tolerance dose with reduced risks of systemic reactions, such as anaphylaxis, need...
Effect of fexofenadine on the quality of life of Japanese cedar pollinosis patients
allergic rhinitis cedar pollinosis daily life fexofenadine quality of life
2010/11/22
Background: The aim of the present survey was to investigate the changes associated with fexofenadine administration in the quality of life (QOL) of Japanese cedar pollinosis patients.
Methods: After...
Clinical aspects of Japanese cedar pollinosis
Japanese cedar pollinosis management pollen survey prevalence risk factor
2010/11/29
Japanese cedar pollinosis (JCPsis) is a major national health problem in Japan. The present review provides an update on information on JCPsis based on clinical data from our research group, through t...