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High Bone Mass in Mice Lacking Cx37 Due to Defective Osteoclast Differentiation
gap junctions connexin37 osteoclast
2014/11/6
Connexin (Cx) proteins are essential for cell differentiation, function and survival in all tissues with Cx43 being the most studied in bone. We now report that Cx37, another member of the connexin fa...
Dynamin Forms a Src Kinase–sensitive Complex with Cbl and Regulates Podosomes and Osteoclast Activity
dynamin osteoclast activity
2014/11/6
Podosomes are highly dynamic actin-containing adhesion structures found in osteoclasts, macrophages, and Rous sarcoma virus (RSV)-transformed fibroblasts. After integrin engagement, Pyk2 recruits Src ...
Titanium Surface Roughness Accelerates RANKL-dependent Differentiation in the Osteoclast Precursor Cell Line,RAW264.7
Titanium Osteoclast Implant
2009/9/14
The present study was a molecular analysis of the initial differentiation of osteoclast precursor RAW264.7 cells on titanium specimens. RAW264.7 cell line was cultured on titanium specimens of which t...
Tissue Inhibitors of Metalloproteinases (TIMP-1 and TIMP-2) Stimulate Osteoclast Differentiation
tissue inhibitors of metalloproteinases (TIMP-1 and TIMP-2) osteoclasts bone marrow culture
2009/5/21
Tissue inhibitor of metalloproteinases-1 (TIMP-1) and TIMP-2, originally known as intrinsic inhibitors of matrix metalloproteinases (MMPs), are now known as constitutive components in serum and have ...
Epidermal Growth Factor in Liposomes May Enhance Osteoclast Recruitment during Tooth Movement in Rats
EGF Liposome Osteoclasts Tooth movement Orthodontic movement
2008/11/6
Objective: To evaluate the effects of local administration of epidermal growth factor (EGF) located within liposomes on recruitment of osteoclasts during mechanical force in rats.Materials and Methods...