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Biporous (macro- and microporous) calcium phosphate gains much attention as a bone substitute material because of its large surface area and that it improves cell penetration. In the present study, we...
The objective of this study was to investigate the regenerative effects of apatite foam (AF) combined with platelet-rich plasma (PRP) on bone defects. Critical-sized defects in the tibia of rats were ...
Our previous in vivo and in vitro studies revealed excellent tissue biocompatibility and osteoconductivity of porous sintered carbonate apatite (CA). The present study focused on the ultrastructural d...
Bioresorption and biocompatibility of carbonate apatites, both sintered and non-sintered (S-CAP and N-CAP) , and of sintered β-tricalcium phosphate (β-TCP) were compared by implanting particles of the...
The purpose of this study was to develop an acrylic resin with antifungal properties by leveraging the photocatalytic activity of apatite-coated titanium dioxide (Ap-TiO2). Candida albicans was used f...
Effects of added α-tricalcium phosphate (α-TCP) and β-TCP were investigated to shed light on the setting reaction of apatite cement (AC) consisting of tetracalcium phosphate (TTCP) and dicalcium phosp...
Tissue response to apatite cement (AC) containing atelocollagen (AC (ate)) was evaluated using conventional AC (c-AC) as a control material. At one week, the only difference between AC (ate) and c-AC ...
We developed a novel apatite coating method that consisted of two-step of chemical treatment: a combined pretreatment of concentrated acid etching and alkaline treatment, followed by alternate soaking...
B-type carbonate apatite (CO3Ap) block may be an ideal artificial bone substitute because it is closer in chemical composition to bone mineral. In the present study, the feasibility to fabricate CO3Ap...
Effects of liquid phase on the basic properties of α-tricalcuim phosphate (α-TCP)-based cement, BIOPEX®, were investigated by employing three liquid phases: distilled water, neutral sodium hydroge...
The aims of this study were to evaluate the effects of CPP method on the crystallinity of apatite powder and on the acid resistance of bovine enamel. Crystallinity degrees of apatite powder before and...
Previously, we developed a poly(lactide-co-glycolide)/nano-hydroxyapatite (PLGA/HA) composite that overcame the limitations of conventional ceramic bone substitutes. This was achieved by introducing a...
To produce carbonate apatite (CAP) ceramics with the desired complex shapes using superplastic deformation, deformation behavior of CAP ceramics under constant loading as well as physical properties a...
Hydroxyapatite and carbonate apatites with different carbonate contents were synthesized, mixed with atelocollagen, and made into sponge scaffolds. The scaffolds were implanted into the bone sockets o...

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