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Luteinizing hormone releasing hormone agonist, [(imBzl)-DHis6,Pro9,NEt]-LHRH (LHRH-A), caused a two to threefold increase in in vitro testosterone (T) secretion by rat Leydig cells. This LHRH-A-indu...
To investigate mechanisms responsible for gonadotropin-releasing hormone (GnRH)-stimulated Leydig cell steroidogenesis, the effects of GnRH agonist [des-Gly10, (D-Ala6) GnRH] on phospholipid turnove...
The present study was designed to elucidate mechanisms responsible for gonadotropin-releasing hormone (GnRH)-stimulated testosterone formation. Purified Leydig cells from adult Sprague-Dawley rats...
A cilio-peristaltic model for pumping of efferent duct (ED) contents that predicts the observed volumetric flow rates and is consistent with a positive pressure gradient toward the epididymis is pro...
We previously reported a strain-related difference in basal 3beta-hydroxysteroid dehydrogenase-isomerase (3betaHSD) activity in response to testosterone in cultured Leydig cells. The data suggested ...
This study examined the potential role of testicular opioids, a pertussis toxin (PT)-sensitive G-protein, and phosphodiesterase in mediating the inhibitory effect of immobilization stress on testi...
Earlier studies on human sperm cryodamage have shown that plasma membrane stress is the primary process and that phospholipid peroxidation in cryopreserved samples is not inhibited by addition of an...
Pretreatment of rats with hormones that suppress testosterone levels and sperm production enhances the recovery of spermatogenesis from stem cells after a cytotoxic insult. It is not known whether t...
To explore the biological characteristics of the recombinant zona pellucida 3 (ZP3) peptides of rhuZP3a22176 and rhuZP3b177348, we examined whether rhuZP3a22176 or rhuZP3b177348 trigger the acros...
Erectile dysfunction (ED) is defined as the inability to achieve or maintain erections sufficient for satisfactory sexual intercourse (NIH Consensus Conference, 1993). It is estimated that the pre...
Androgens are deemed to be critical for the development, growth, and maintenance of penile tissue as well as for erectile function. Androgens are also reported to inhibit differentiation of stroma p...

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