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Effects of subchronic treatment with cis-platinum on testicular function, fertility, pregnancy outcome, and progeny
Fertility cis-platinum pregnancy outcome progeny
2009/2/10
Cis-platinum-based chemotherapy is known to impair spermatogenesis, but the effects of paternal cis-platinum treatment on the progeny are unknown. To study this effect, sexually mature male Sprague-...
A Retrospective Comparison of Pregnancy Outcome Following Conventional Oocyte Insemination vs Intracytoplasmic Sperm Injection for Isolated Abnormalities in Sperm Morphology Using Strict Criteria
In vitro fertilization zona pellucida subfertile male
2008/12/24
Initial in vitro fertilization (IVF)–embryo transfer studies found poor fertilization and pregnancy rates following conventional fertilization of oocytes when using sperm with <4% normal morpholo...
5-Aza-2'-Deoxycytidine Induces Alterations in Murine Spermatogenesis and Pregnancy Outcome
DNA methylation 5-azacytidine DNMT DNMT1 mouse fertility DNA methyltransferase
2008/12/19
Because of the ability of cytidine analogues, such as 5-aza-2'-deoxycytidine, to incorporate into DNA and lead to decreases in DNA methylation, there has recently been renewed interest in using thes...