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Oxidative stress differentially regulates the expression of gamma-glutamyl transpeptidase mRNAs in the initial segment of the rat epididymis
gamma-glutamyl transpeptidase mRNAs initial segment rat epididymis
2009/2/17
Reactive oxygen species (ROS) have a powerful cytotoxic effect on spermatozoa and have been implicated in spermatozoal dysfunction and male infertility. gamma-Glutamyl transpeptidase (GGT) is esse...
Oxidative stress and male infertility
Seminal plasma reactive oxygen species antioxidants infertility
2009/2/16
We have studied the activity of substances (superoxide dismutase [SOD], catalase [Cat], malonaldehyde, xanthine oxidase [XO], nitric oxide [NOx]) participating in oxidative stress. Seminal plasma sa...
Role of oxidative stress and antioxidants in male infertility
oxidative stress antioxidants male infertility
2009/2/13
Oxygen toxicity is an inherent challenge to aerobic life, including spermatozoa, the cells responsible for propagation of the species. How this toxicity affects the spermatozoan in its interactions wi...
Leukocytic infiltration into the human ejaculate and its association with semen quality, oxidative stress, and sperm function
Leukocytes reactive oxygen species sperm function
2009/2/12
Immunocytochemical techniques have been used to monitor the size and composition of the leukocyte population in unfractionated human semen samples and sperm populations generated by Percoll gradie...
Relationship between seminal white blood cell counts and oxidative stress in men treated at an infertility clinic
Leukocytospermia male infertility semen reactive oxygen
2008/12/29
In semen, granulocytes are major producers of reactive oxygen species (ROS), which can damage sperm. The diagnosis of leukocytospermia is usually based on the World Health Organization (WHO) definitio...
Oxidative stress in normospermic men undergoing infertility evaluation
Oxidative stress normospermic men infertility evaluation
2008/12/26
The purpose of this study was to determine whether normospermic infertile men have high seminal oxidative stress, using 3 measures of oxidative stress: reactive oxygen species (ROS), total antioxidant...
Nitric oxide induces oxidative stress and mediates cytotoxicity to human cavernosal cells in culture
Nitric oxide mediates cytotoxicity human cavernosal cells
2008/12/26
Nitric oxide (NO) is a product of nitric oxide synthase (NOS) activity and is recognized as the main mediator of penile erection by induction of cavernosal smooth muscle relaxation. Although excessive...
Oxidative stress in prostatic fluid of patients with chronic pelvic pain syndrome：correlation with gram positive bacterial growth and treatment response
Oxidative stress prostatic patients chronic pelvic pain syndrome
2008/12/25
The etiology of chronic pelvic pain syndrome (CPPS)/chronic prostatitis category III remains unknown. Whereas a subset of men respond to antimicrobial therapy, gram positive bacteria isolated from...
Inflammatory mediators exert toxic effects of oxidative stress on human spermatozoa
Inflammatory factors reactive oxygen species peroxidative damage semen
2008/12/24
Epidemiological studies regarding male infertility have revealed that more and more infertile men suffer from acute or chronic inflammation of the genitourinary tract, which often occurs witho...
Induction of Oxidative Stress by Organic Hydroperoxides in Testis and Epididymal Sperm of Rats In Vivo
Rat testis lipid peroxidation ROS levels antioxidant defenses DNA damage
2008/12/24
The present study describes the extent and pattern of oxidative stress induction in testis and epididymal sperm of rats following in vivo exposure to repeated sublethal doses of 2 model pro-oxidant...
Role of Oxidative Stress in the Pathophysiological Mechanism of Erectile Dysfunction
Oxidative Stress Pathophysiological Mechanism Erectile Dysfunction
2008/12/24
Erectile dysfunction (ED) is defined as the inability to achieve or maintain erections sufficient for satisfactory sexual intercourse (NIH Consensus Conference, 1993). It is estimated that the pre...
The greatest paradox of aerobic respiration is that oxygen, which is essential for energy production, may also be detrimental because it leads to the production of reactive oxygen species (ROS) (S...
Nickel-Induced Oxidative Stress in Testis of Mice：Evidence of DNA Damage and Genotoxic Effects
Nickel chloride oxidative damage apoptosis abnormal sperms dominant lethal mutations
2008/12/22
Oxidative stress (OS) mechanisms are speculated to play a significant role in nickel-induced toxic effects and their carcinogenic potency. Although nickel-induced oxidative damage in somatic tissues...
Oxidative Stress and Antioxidant Therapy：Their Impact in Diabetes-Associated Erectile Dysfunction
Impotence vitamin E sildenafil nitric oxide phosphodiesterase type
2008/12/22
Oxidative stress is believed to affect the development of diabetic-associated vasculopathy, endothelial dysfunction, and neuropathy within erectile tissue. Our hypothesis is that, given adequate con...
Role of Oxidative Stress and Antioxidants in Andrology and Assisted Reproductive Technology
Oxidative Stress Antioxidants Andrology Assisted Reproductive Technology
2008/12/19
Twenty-five years ago the first human, Louise Brown, was conceived outside the body, and this event created a new milestone in the history of mankind and the concept of human in vitro fertilization (I...