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Worldwide, dietary guidelines have adopted the recommendation of consuming whole grain as part of a healthy diet. Ideally, dietary guidelines are based on convincing evidence, established by multiple ...
Although current dietary guidelines for Americans recommend increased intake of grain products to prevent coronary heart disease (CHD), epidemiologic data relating wholegrain intake to the risk of ...
Background: Epidemiology associates whole-grain (WG) consumption with several health benefits. Mounting evidence suggests that WG wheat polyphenols play a role in mechanisms underlying health benefits...
Background: Whole-grain foods are associated in observational studies with a lower body mass index and lower cardiovascular disease (CVD) risk. However, few clinical trials have tested whether incorpo...
Background: Whether the intake of dietary fiber can protect against colorectal cancer is a long-standing question of considerable public health import, but the epidemiologic evidence has been inconsis...
Background: It has recently been shown that oxidative stress, infection, and inflammation are predominant pathophysiologic factors for several major diseases. Objective: We investigated the associatio...
Background: Whole-grain intake has been shown to be inversely associated with cardiovascular events, but an association with atherosclerosis is less well established. Objective: We sought to evaluate ...
Three 4-wk interventions were undertaken in a randomized crossover design with 28 overweight men aged 40–65 y who had no history of bowel disease. Against a background intake of 14 g dietary fiber (DF...
Epidemiologic evidence of a preventive effect of whole grain against type 2 diabetes is mainly based on data from women. Information specific to men and women is needed.
Tracing the historical development of a scientific concept is a difficult and often subjective exercise. In the field of dietary research, however, the possibility that something of physiologic import...
Increased intake of whole-grain foods has been related to a reduced risk of developing diabetes and heart disease. One underlying pathway for this relation may be increased insulin sensitivity.
Recent epidemiologic study results showed that subjects who had high intakes of whole-grain foods had lower risks of death and heart disease than did subjects who had low intakes. However, the finding...
Background: Certain dietary components may play a role in the prevention of type 2 diabetes.Objective: We examined prospectively the associations between whole- and refined-grain intake and ...
Background: The influence of whole grains on cardiovascular disease risk may be mediated through multiple pathways, eg, a reduction in blood lipids and blood pressure, an enhancement of insulin s...

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