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We read with great interest the article by Hume et al. (1), “Low energy intake plus low energy expenditure (low energy flux), not energy surfeit, predicts future body fat gain.” The study used the ene...
During the past 2 y the leptin field has continued to expand rapidly (from 600 to >2000 citations currently in the MEDLINE database), extending leptin biology into areas well beyond feeding behavior a...
The striking excess of obesity in US black women has been observed for decades (1) and continues to be reconfirmed (2). When consideration of obesity prevalence is expanded to include men and other...
Clinicians often recommend an additional energy intake of 1250 kJ/d to their pregnant patients. Previous studies have shown considerable variation in the metabolic response to pregnancy and thus in...
In 1995, we described a new model for adiposity regulation. Since then, data regarding the biology of body weight regulation has accumulated at a remarkable rate and has both modified and strengthe...
The prevalence of obesity has increased dramatically in recent years in the United States, with similar patterns seen in several other countries. Although there are several potential explanations for ...

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