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近日,复旦大学生物医学研究院许杰课题组分别在Oncogene和RSC Chemical Biology期刊发表研究论文,报道氨氯地平(amlodipine)对PD-L1的诱导自噬降解作用,以及PD1-PALM对PD-1的靶向降解作用。
天津大学药学院尉迟之光团队及国际合作团队在Nature Chemical Biology发文揭示双酰胺类药剂激活鱼尼丁受体的分子机理(图)
天津大学药学院 尉迟之光 双酰胺类药剂 鱼尼丁受体 分子机理
2020/8/25
2020年8月17日,天津大学尉迟之光团队和加拿大英属哥伦比亚大学Filip Van Petegem团队合作在Nature Chemical Biology发表了题为Structural basis for diamide modulation of ryanodine receptor的研究论文,首次阐明了双酰胺类药剂与鱼尼丁受体结合的结构基础,为进一步理解双酰胺的作用机理以及抗药性产生的机制提...
2017药物化学和化学生物学研讨会(Symposia on Medicinal Chemistry and Chemical Biology)
2017 药物化学和化学生物学 研讨会
2017/1/13
Medicinal chemistry and chemical biology are stimulating fields that connect many scientific disciplines and allow for collaboration with other scientists in a wide variety of opportunities. The objec...
The Integration of Basic Cell Biology Concepts Into the Practice of Pharmacy
cell biology physiology microtubules endocytosis exocytosis
2018/3/22
Human Anatomy, Physiology and Pathology I (PHBMS 355) is an integrated course that covers the fundamentals of human anatomy, physiology, and pathology. This is a required 4-credit course that has an a...
A Biotechnology Course Emphasizing Molecular Biology and Practical Experience
Biotechnology Course Emphasizing Molecular Biology Practical Experience
2016/3/10
This article describes a new course offered to graduate and undergraduate students (in an all PharmD program) at Mercer University School of Pharmacy. The primary objective of this course is to prepar...