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Effects of Collagen Gel Stiffness on Cdc42 Activities of Endothelial Colony Forming Cells during Early Vacuole Formation
ECFC Vacuole Cdc42 Stiffness FRET
2015/1/12
Recent preclinical reports have provided evidence that endothelial colony forming cells (ECFCs), a subset of endothelial progenitor cells, significantly improve vessel formation, largely due to their ...
Adipose stromal cells enhance keratinocyte survival and migration in vitro, and graft revascularization in mouse wound healing model
ASC adipose stromal cell wound healing Integra burn adipose stem cell keratinocyte endothelial cell
2015/1/12
In the US, more than 1 million burn injuries are reported annually. About 45,000 injuries due to fires and burns result in hospitalization and ten percent of these result in death every year. Advances...
The Response of Endothelial Cells to Fluid Shear Stress Using a Co-Culture Model of the Arterial Wall
Endothelial Cell Mechanical Stimulation Proliferation Smooth Muscle Cell Vascular Tissue Engineering
2010/1/7
An endothelial cell (EC) smooth muscle cell (SMC) co-culture
model of the arterial wall was used to study the effect of fluid shear
stress on EC behavior. This model, in addition to being a more rea...
Endothelial cells influence the osteogenic potential of bone marrow stromal cells
Endothelial cells the osteogenic potential bone marrow stromal cells
2010/2/25
Improved understanding of the interactions between bone cells and endothelial cells involved in osteogenesis should aid the development of new strategies for bone tissue engineering. The aim of the pr...
Novel models of cancer-related anemia in mice inoculated with IL-6-producing tumor cells
Novel models cancer-related anemia mice inoculated IL-6-producing tumor cells
2009/5/8
We established models of cancer-related anemia in mice from subcutaneous inoculation of two IL-6-producing cancer cell lines, human lung cancer cell line LC-06-JCK and murine colon26 clone 5 colon c...
DNA microarray analysis of changes in gene expression induced by 1,25-dihydroxyvitamin D3 in human promyelocytic leukemia HL-60 cells
DNA microarray analysis gene expression 1,25-dihydroxyvitamin D3 promyelocytic leukemia HL-60 cells
2009/3/2
Using a DNA microarray, we analyzed about 16,600 genes for changes in expression associated with the differentiation of human promyelocytic leukemia HL-60 cells induced by 1α,25-dihydroxyvitamin D3 ...
Ca2+/calmodulin-dependent cyclic nucleotide phosphodiesterase in cGMP metabolism in rabbit parotid acinar cells
Ca2+/calmodulin-dependent cyclic nucleotide phosphodiesterase cGMP metabolism rabbit parotid acinar cells
2009/3/2
Muscarinic cholinergic receptor activation provokes cGMP formation in parotid acinar cells. We investigated the involvement of Ca2+/calmodulin-dependent cyclic nucleotide phosphodiesterase (PDE1) in...
IL-1β stimulates urokinase-type plasminogen activator expression and secretion in human dental pulp cells
IL-1β stimulates urokinase-type plasminogen activator expression secretion human dental pulp cells
2009/3/2
Plasminogen activator (PA) is the enzyme that converts plasminogen to its active form, plasmin, which is involved in various physiological and pathological phenomena. The conversion is catalyzed by ...
Changes of HCN gene expression and If currents in Nkx2.5-positive cardiomyocytes derived from murine embryonic stem cells during differentiation
HCN gene expression Nkx2.5-positive cardiomyocytes murine embryonic stem cells
2009/3/2
Changes in the expression of hyperpolarization-activated cyclic nucleotide (HCN)-gated channels and If currents during the differentiation of embryonic stem cells into cardiac cells remain unknown. ...
Period is involved in the proliferation of human pancreatic MIA-PaCa2 cancer cells by TNF-α
proliferation human pancreatic MIA-PaCa2 cancer cells TNF-α
2009/3/2
Recent studies have found alterations to clock genes in several forms of cancer. Period (Per) gene plays an important role in the circadian system, the cell cycle, the induction of apoptosis, and DN...
Cyclooxygenase-2 induction by lysophosphatidylcholine in cultured rat vascular smooth muscle cells：involvement of the p38MAPK pathway
Cyclooxygenase-2 lysophosphatidylcholine cultured rat vascular smooth muscle cells
2009/3/2
Lysophosphatidylcholine (lysoPC) stimulates the release of prostaglandins (PGs) in various cells and tissues. Cyclooxygenase (COX)-2 has recently emerged as a key regulator of PG synthesis. We inves...
In vitro and in vivo effects of rat kidney vascular endothelial cells on osteogenesis of rat bone marrow mesenchymal stem cells growing on polylactide-glycoli acid (PLGA) scaffolds
rat kidney vascular endothelial cells rat bone marrow mesenchymal stem cells polylactide-glycoli acid (PLGA) scaffolds
2010/2/25
It is well established that vascularization is critical for osteogenesis. However, adequate vascularization also remains one of the major challenges in tissue engineering of bone. This problem is furt...