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Huge libraries of drug compounds may hold potential treatments for a variety of diseases, such as cancer or heart disease. Ideally, scientists would like to experimentally test each of these compounds...
With the release of platforms like DALL-E 2 and Midjourney, diffusion generative models have achieved mainstream popularity, owing to their ability to generate a series of absurd, breathtaking, and of...
A novel tissue-engineered 3D tumor model for anti-cancer drug discovery
decellularized porcine lung matrix breast tumor model biocompatibility CARS drug resistance
2023/3/1
Cancer biology and drug discovery are heavily dependent on conventional 2D cell culture systems. However, a 2D culture is significantly limited by its ability to reflect 'true biology' of tumor in viv...
《个性化药物： 新药研发的未来Personalized medicines, the future of drug discovery》
个性化药物 上海科学技术文献出版 上海药物研究所
2023/2/21
个性化药物： 新药研发的未来Personalized medicines, the future of drug discovery
上海市肿瘤研究所金浩杰研究员和Rene Bernards院士合作在Nature Reviews Drug Discovery杂志发表长篇综述文章：癌症联合靶向治疗的背景、优势与挑战（图）
金浩杰研究员 癌症 肿瘤药物 肿瘤细胞
2023/1/13
近日，上海市肿瘤研究所金浩杰研究员与René Bernards院士作为共同通讯作者在Nature Reviews Drug Discovery期刊上发表了长篇综述文章“Rational combinations of targeted cancer therapies: background, advances and challenges”，对癌症联合靶向治疗策略的背景、优势及面临的挑战进行全面...
Over the past few decades, very few new antibiotics have been developed, largely because current methods for screening potential drugs are prohibitively expensive and time-consuming. One promising new...
In their quest to discover effective new medicines, scientists search for drug-like molecules that can attach to disease-causing proteins and change their functionality. It is crucial that they know t...
NSF provides support for drug discovery platform for hard-to-treat cancers（图）
NSF provides support drug discovery platform hard-to-treat cancers
2020/5/9
A new round of support will help a Purdue University-affiliated startup further develop a platform designed to create drugs for people with hard-to-treat cancers.Akanocure Pharmaceuticals, Inc., ...
AI accelerating drug discovery to fight COVID-19（图）
AI accelerating drug discovery fight COVID-19
2020/5/9
Researchers are running a global race to discover a vaccine, drug or combination of treatments that can disrupt the SARS-CoV-2 virus, which causes the COVID-19 disease, and prevent widespread deaths.M...
中山大学孙逸仙纪念医院宋尔卫教授团队研究论文在Nature Reviews Drug Discovery发表：化敌为友——靶向肿瘤相关成纤维细胞（图）
中山大学孙逸仙纪念医院 宋尔卫 研究论文 靶向肿瘤 纤维细胞
2019/1/18
肿瘤相关成纤维细胞(CAFs)通常是肿瘤微环境中最丰富的间质细胞，在肿瘤进展过程起着重要的作用。这提示CAFs可能成为恶性肿瘤治疗的理想靶点。2018年11月23日，我校孙逸仙纪念医院宋尔卫教授团队在Nature Reviews Drug Discovery（IF=50.17）在线发表了题为“Turning foes to friends: targeting cancer-associated ...
The Gordon Research Seminar on Preclinical Form and Formulation for Drug Discovery
Drug Discovery Preclinical Form
2017/3/7
Applications for this meeting must be submitted by May 6, 2017. Please apply early, as some meetings become oversubscribed (full) before this deadline. If the meeting is oversubscribed, it will be sta...
2017年结核药物发现和发展高登研究研讨会（The Gordon Research Seminar on Tuberculosis Drug Discovery and Development）
Tuberculosis Drug Discovery
2017/3/7
Applications for this meeting must be submitted by May 27, 2017. Please apply early, as some meetings become oversubscribed (full) before this deadline. If the meeting is oversubscribed, it will be st...
The aim of the 6th RSC-BMCS Fragment-based Drug Discovery meeting will be to continue the focus on case studies in Fragment-based Drug Discovery that have delivered compounds to late stage medicinal c...
第二次药物发现转运体研讨会（The 2nd Symposium on Transporters in Drug Discovery）
structural biology Drug Discovery
2017/1/19
Cell surface transporters play a key role in human health and disease, both through their impact on drug disposition and as therapeutic targets in their own right. This meeting continues on from the...
The 2017 Gordon Research Conference on Preclinical Form & Formulation for Drug Discovery
Preclinical Form Formulation Drug Discovery
2017/1/18
The 2017 Preclinical Form and Formulation for Drug Discovery Gordon Research Conference will present cutting-edge research on evaluation of appropriate form and enabling formulations for drug candidat...