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南京农业大学农学院《The Plant Journal》发表油菜遗传育种团队“Mutation to a cytochrome P450-like gene alters the leaf color by affecting the heme and chlorophyll biosynthesis pathways in Brassica napus”（图）
油菜遗传育种 叶绿素 生物合成
2023/10/28
2023年7月28日，The Plant Journal在线发表了南京农业大学作物遗传与种质创新利用全国重点实验室油菜遗传育种团队的最新研究成果“Mutation to a cytochrome P450-like gene alters the leaf color by affecting the heme and chlorophyll biosynthesis pathways in Br...
Expression and Purification of the Recombinant Cytochrome P450 CYP141 Protein of Mycobacterium Tuberculosis as a Diagnostic Tool and Vaccine Production
Gene Expression Cytochrome P450 Enzyme System Mycobacterium Tuberculosis
2015/11/6
Background: Tuberculosis (TB) is regarded as a health problem worldwide, particularly in developing countries. Mycobacterium tuberculosis (M. tuberculosis) is the cause of this disease. Approximately ...
Cloning of the Recombinant Cytochrome P450 Cyp141 Protein of Mycobacterium tuberculosis as a Diagnostic Target and Vaccine Candidate
Cloning Cytochrome Mycobacterium Tuberculosis Diagnostic
2015/10/15
Background: Tuberculosis has been announced as a global emergency by World Health Organization and the second infectious agent of mortality worldwide. The general policy in the development of new vacc...
Impact of cytochrome P450 2C19*2 polymorphism on the clinical cardiovascular events after stent implantation in patients receiving clopidogrel of a southern Tunisian region
Clopidogrel CYP2C19*2 Polymorphism MACE Stent Thrombus
2013/2/19
Introduction: The concept of clopidogrel resistance, first described in biology is being strengthened by recent data from clinical epidemiology. The cardiologists have been sensitized to this concept ...
This study was conducted to investigate the effect of the ergot alkaloid, ergotamine (ET), on the induction of CYP3A and the interaction in vivo and in vitro with ET. Sprague-Dawley rats were treated ...
Liver cytochrome P450 system as affected by endophyte-infected tall fescue seed extracts and ergot alkaloids
Seed Extract Tall Fescue CYP3A4 Ergot Alkaloid
2013/2/27
Endophyte infected tall fescue (E+) is the base diet for nearly all beef cattle in the southern USA. It has been linked to a variety of toxicological conditions due to the presence of large numbers of...
Ligninolytic Peroxidase-Like Activity of a Synthetic Metalloporphine Immobilized onto Mercapto-Grafted Crosslinked PVA Inspired by the Active Site of Cytochrome P450（图）
porphine porphyrin lignin peroxidase cytochrome P450 biomimetic
2013/10/10
A synthetic metalloporphine was immobilized onto a PVA-based and mercapto-grafted solid support, emulating the active site of cytochrome P450. Its ligninolytic peroxidase-like catalytic activity was s...
Cytochrome P450 Induction and Gene Expression in Channel Catfish (Ictalurus Punctatus) Following Wastewater Treatment Plant Effluent Exposure in Field and Laboratory Settings
EROD CYP1B Molecular Biomarker Channel Catfish Liver Monooxygenases MFO
2013/3/13
The objectives of this study were as follows: 1) to establish a baseline ethoxyresorufin-O-deethylase (EROD) activity level in channel catfish (Ictalurus punctatus), 2) to assess changes in induction ...
Effect of Estradiol and Nonylphenol on mRNA Expression of Estrogen Receptors α and β,and Cytochrome P450 Aromatase in the Gonad of Chicken Embryos
p-nonylphenol ERα ERβ P450arom endocrine disruptor
2009/7/31
Effects of estradiol-17β (E2) and p-nonylphenol (NP) on mRNA expression of estrogen receptor α (ERα), estrogen receptor β (ERβ) and cytochrome P450 aromatase (P450arom) were examined in the early stag...
mRNA Expression of Cytochrome P450 17αhydroxylase,Cytochrome P450 Aromatase,Anti-Müllerian Hormone, Estrogen Receptor α,and Androgen Receptor in Developing Gonads of Japanese Quail
gene expression gonad Japanese quail
2009/7/30
Japanese quail (Coturnix coturnix japonica) is widely used in avian reproduction tests and avian sex reversal screening tests for evaluating adverse effects of endocrine disrupting chemicals (EDCs). H...
Cloning of a Cytochrome P450 Gene Induced by Ethylene Treatment in Deepwater Rice (Oryza sativa L.)
Cytochrome P450 Deepwater rice Differential display Ethylene Internode elongation
2009/7/21
Cloning of a Cytochrome P450 Gene Induced by Ethylene Treatment in Deepwater Rice (Oryza sativa L.)
Role of Cytochrome P450 in Mechanism of Pyrethroid Resistance
cytochrome P450 monooxygenases pyrethroids Culex quinquefasciatus insecticide resistance
2009/3/7
Cytochrome P450 monooxygenases are important metabolic enzymes involved in catalyzing a number of compounds and thus are essential for most creatures. One of the major roles of P450s in insects is d...
Effect of Flavonoids on Glutathione Level,Lipid Peroxidation and Cytochrome P450 CYP1A1
flavonoids tumor cells cytotoxicity
2009/3/5
Flavonoids are phytochemicals exhibiting a wide range of biological activities, among which are antioxidant activity, the ability to modulate activity of several enzymes or cell receptors and possibil...
Abnormal Morphology of Spermatozoa in Cytochrome P450 17-hydroxylase/17, 20-lyase（CYP17）Deficient Mice
Gene deletion steroidogenesis mitochondria architecture fertility
2008/12/24
Cytochrome P450 17-hydroxylase/17, 20-lyase (CYP17) is crucial for cortisol and sex steroid biosynthesis. In a previous study we examined CYP17 function by generating mice with a targeted CYP17 d...
Differential Expression of Cytochrome P450 Genes Regulate the Level of Adipose Arachidonic Acid in Sus Scrofa
Arachidonic Acid Cytochrome P450 Gene Expression Adipose Tissue Sus scrofa
2016/4/28
We compared the fatty acid composition of adipose tissues prepared from Korean native and Yorkshire pigs that have different characteristics in growth and fat deposition. There was no significant diff...