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【应化系学术报告2023-03】From DNA damage to DNA sensing: bridging innate and adaptive immunity（图）
DNA damage DNA sensing innate adaptive immunity
2023/6/20
【应化系学术报告2023-03】From DNA damage to DNA sensing: bridging innate and adaptive immunity
SMC5/6 Complex Subunit NSE4A is Involved in DNA Damage Repair and Seed Development in Arabidopsis
Seed Development DNA Damage NSE4A subunit SMC5/6 Complex
2024/3/4
The maintenance of genome integrity over cell divisions is critical for plant development and the correct transmission of genetic information to the progeny. A key factor involved in this process is t...
第八届DNA损伤应答与人类疾病国际研讨会（isDDRHD-2017）（8th international symposium on DNA Damage Response&Human Disease）
第八届 DNA损伤应答与人类疾病 国际研讨会
2017/8/31
第八届DNA损伤应答与人类疾病国际研讨会（international symposium on DNA Damage Response & Human Disease, isDDRHD-2017）将于2017年10月27-29日在深圳大学召开。DNA损伤应答与人类疾病国际研讨会（isDDRHD）是由许兴智教授和Zhao-Qi Wang院士于2010年共同发起，旨在为DNA修复领域的中国学者与国际主...
Spatially localized generation of nucleotide sequence-specific DNA damage
sperm chemotaxis fertilization TPX-1 AEG CRISP
2016/5/23
Psoralens linked to triplex-forming oligonucleotides (psoTFOs) have been used in conjunction with laser-induced two-photon excitation (TPE) to damage a specific DNA target sequence. To demonstrate tha...
DNA damage of blood lymphocytes and neutrophils in cattle with lymphosarcoma
apoptosis cattle lymphocytes lymphosarcoma neutrophils
2015/4/15
The objective of the present study was to analyze the apoptotic process in peripheral blood mononuclear cells (PBMC) and polymorphonuclear neutrophil leukocytes (PMN) in cows clinically affected with ...
The Role Of ERα, ERβ And Phytoestrogens From Soy In P53- Mediated Response To Dna Damage In Mammary Epithelium
Biological sciences Breast cancer Estrogen receptors Mammary tumors p53 Phytoestrogens DNA damage
2014/12/11
Estrogenic compounds can stimulate proliferation of the mammary epithelium, but also potentiate the activity of the p53 tumor suppressor protein. These contradictory activities of estrogenic compounds...
Abstract: This paper is devoted to the analysis of the complex damage of DNA irradiated by ions. The analysis and assessment of complex damage is important because cells in which it occurs are less li...
Level of DNA Damage in Lead-Exposed Workers
lead comet assay DNA damage occupational exposure
2010/12/22
Lead plays a significant role in modern industry. This metal is related to a broad range of physiological, biochemical and behavioural dysfunctions. The genotoxic effects of lead have been studied bot...
IS CONCENTRATION AND MOTILITY OF MALE GAMETES RELATED TO DNA DAMAGE MEASURED BY COMET ASSAY?
spermatozoa DNA damage Comet assay quality of sperm
2010/12/22
Approximately 8% of couples in the World have problem with offspring production.Male infertility, which is the reason of the half of reproduction failures, is connected with diminished sperm productio...
Study of DNA damage induced by dental bleaching agents in vitro
CHO cells Comet assay Tooth bleaching Mutagenicity tests
2009/10/19
Dental bleaching is a simple and conservative procedure for aesthetic restoration of vital and non-vital discolored teeth. Nevertheless, a number of studies have demonstrated the risk of tissue damage...
A Preliminary Study of DNA Damage in Peripheral Lymphocytes from Lung Cancer Patients and Healthy Subjects
Comet assay DNA damage Lung cancer Lymphocyte
2009/6/24
A pilot study was undertaken to investigate the differences in oxidative DNA damage and 2-h DNA repair in peripheral lymphocytes between lung cancer patients and healthy subjects. Twenty-four lung ca...
Protective Effects of Melanoidins Derived from Soy Sauce and Soy Paste on NO-Induced DNA Damage
melanoidin DNA damage comet assay
2009/6/17
We determined the protective activity of melanoidins against DNA damage using the comet assay. We used nitric oxide (NO) as a DNA damaging agent and HL60 (human promyelocytic leukemic cell line). Mela...
Genetic Studies of Bone Diseases: Evidence for Involvement of DNA Damage Response Proteins in Bone Remodeling
p53 Atm c-Abl osterix osteoblast osteoporosis
2009/4/20
Bone remodeling is carried out by bone marrow mesenchymal stem cell derived osteoblasts, which form the bones, and hematopoeitic stem cell derived osteoclasts, which absorb the bones. Their actions a...
Localization of oxidative DNA damage after Au injection and effects of Au on Cp in renal kidney
Gold (Au) Copper (Cu) Ceruloplasmin (Cp) 8-hydroxydeoxyguanosine (8-OHdG) Metallotionein (MT)
2009/4/1
The present study was carried out to investigate the effect of gold (Au) injection on copper (Cu) and two types of ceruloplasmin (Cp), total Cp (ID1) and active Cp (ID2), metallothionein (MT) in the s...
Mechanisms of the DNA Damage in Rat Kidney after Au Injection
Gold (Au) Copper (Cu) 8-hydroxydeoxyguanosine (8-OHdG) DNA damage Metallothionein (MT)
2009/3/16
Au (gold) is a heavy metal and its complexes are one of the more effective medicaments available for rheumatoid arthritis, although many authors have reported serious kidney damage during the chrysoth...