搜索结果: 1-15 共查到“GnRH-a”相关记录63条 . 查询时间(0.1 秒)
探讨出血性脑卒中病人血浆和脑脊液β-内啡肽、促性腺激素释放激素（GnRH）、一氧化氮（NO）、降钙素基因相关肽（CGRP）的变化及意义。方法 选取2017年6月至2018年12月收治的高血压性脑出血（HICH）80例为HICH组，自发性蛛网膜下腔出血（SAH）52例为SAH组，以无神经系统疾病40例为对照组。检测血浆和脑脊液β-内啡肽、GnRH、CGRP、NO水平。
观察复方大血藤灌肠剂与促性腺激素释放激素激动剂（GnRH-a）各自单用及联合应用对腹腔镜保守手术后子宫内膜异位症（EMs）患者的临床疗效。方法 选取2015年1月—2017年3月经浙江省中医院腹腔镜确诊并行保守手术的瘀热互结型EMs患者65例，随机分为单纯复方大血藤组18例（术后予复方大血藤灌肠剂保留灌肠）、单纯GnRH-a治疗组24例（术后予GnRH-a治疗）、联合治疗组23例（术后复方大血藤灌...
一种新型口服GnRH拮抗剂——Elagolix
Elagolix 子宫内膜异位症 促性腺素释放激素
2018/12/14
艾伯维（AbbVie）于2017年9月6日向美国食品药品监督管理局（FDA）提交了将Elagolix用于治疗子宫内膜异位症的新药申请，并在1个多月后获得了FDA的优先审评资格。Elagolix是一种口服的促性腺激素释放激素拮抗剂（GnRHA），对于子宫内膜异位症引起的月经痛和非月经盆腔痛具有很好的疗效。与以往大家所熟知的GnRH激动剂（GnRHa）相比，具有较高的口服生物利用度，避免了注射引起的疼...
GnRH类似物联合化疗对绝经前女性卵巢功能保护的Meta分析
肿瘤 卵巢功能早衰 抗肿瘤联合化疗方案 促性腺素释放激素类似物
2018/12/18
目的：探讨在化疗过程中促性腺激素释放激素（GnRH）类似物对绝经前女性卵巢功能的保护。方法：计算机检索PubMed、EMbase、Cochrane Library、中国知识资源总库（CNKI系列数据库）、中国生物医学文献数据库（CBM）、维普数据库、万方数据库，检索时间2000年1月—2017年7月。全面收集GnRH类似物联合化疗对绝经前女性卵巢功能影响的临床试验，采用Cochrane系统评价的方...
旨在探讨GnRH主动免疫雌性SD大鼠的调控机制。24只雌性SD大鼠随机分为免疫组、卵巢切除组和空白对照组（n=8），免疫组于12周龄注射疫苗，4周后加免；卵巢切除组11周龄外科手术摘除卵巢；空白对照组不作任何处理。使用放射免疫分析法测定血清激素E2、P4、FSH和LH含量，荧光定量PCR分析各基因mRNA表达情况。结果显示，主动免疫显著降低血清E2、P4、FSH和LH含量，至56周处死时，E2和L...
旨在研究GnRH和GnIH基因和激素在鹅繁殖过程中的重要作用，本研究以产蛋性能差异显著的四川白鹅和溆浦鹅为试验材料，利用Real-time RCR方法检测产蛋前期、产蛋期和休产期两种鹅的下丘脑、垂体和卵巢组织中GnRH和GnIH mRNA的表达量；利用放射性免疫和酶联免疫吸附测定法测定血清中的GnRH和GnIH激素变化情况。结果表明：GnRH和GnIH基因在四川白鹅和溆浦鹅的下丘脑、垂体和卵巢组织...
GnRH主动免疫对公猪体内粪臭素代谢的影响
GnRH主动免疫 肝 粪臭素代谢 公猪膻味
2016/6/22
旨在探讨促性腺激素释放激素(Gonadotropin releasing hormone，GnRH)主动免疫对公猪体内粪臭素代谢的影响。36只公猪随机分为免疫组（10周龄时初免，18周龄加免）、手术去势组（1周龄外科阉割）及完整对照组（不作任何处理）。应用ELISA检测血清中睾酮、雌二醇及雄烯酮含量，采用高效液相色谱检测脂肪中粪臭素、雄烯酮和血液中雄烯酮含量，荧光定量PCR检测肝中粪臭素代谢相关基...
Serotonin, GnRH-A, and dopamine interaction in the control of in vivo luteinizing hormone release in Prussian carp (Carassius gibelio Bloch) at the time of gonad recrudescence
gonadotropin-releasing hormone analoque LH
2015/7/7
The effects of serotonin (5-HT), GnRH analogue (D-Ala6
LHRH, GnRH-A) and dopamine
antagonist – pimozide (PIM), on luteinizing hormone (LH) release in mature Prussian carp female (Carassius
gibel...
Effects of GnRH agonist immunization on vaginal electrical resistance, FSH, LH, and ovaries in prepubertal female sheep
gonadotropin-releasing hormone agonist gonadotropins vaginal electrical resistance follicle development ewe
2015/6/24
The study is aimed at the investigation of the effects of GnRH agonist (alarelin) immunization on the vaginal electrical resistance (VER) and secretion of FSH and LH in sheep. Forty-two prepubertal fe...
Effects of GnRH, PGF2α and oxytocin treatments on conception rate at the time of artificial insemination in lactating dairy cows
cow spontaneous oestrus GnRH PGF2伪 oxytocin pregnancy
2015/6/9
In several studies, hormones such as gonadotropin-releasing hormone (GnRH), prostaglandins and oxytocin were used to increase pregnancy rate by inducing ovulation and improving the sperm transport in ...
Superovulation following follicular synchronization with GnRH at random stages of the oestrous cycle in heifers
oestrous cycle GnRH superstimulation follicular puncture heifer
2015/6/9
The objective of this study was to develop a superovulatory program based on synchronization of follicular waves with GnRH which could be applied regardless of the stage of the oestrous cycle. 36 heif...
Superovulation following follicular synchronization with GnRH at random stages of the oestrous cycle in heifers: oocyte competence and in vitro embryo production
heifer oocyte GnRH oocyte competence
2015/6/8
The objective of this study was to develop a superovulatory program based on the synchronization of follicular waves with GnRH which could be applied regardless of the stage of the oestrous cycle. In ...
LH secretion and 17ββ-estradiol concentration in the blood plasma and hypothalamus of goldfish (Carassius auratus gibelio B.) and common carp (Cyprinus carpio L.) treated with fadrozole (aromatase inhibitor) and GnRH analogues
aromatase inhibitor LH estradiol goldfish carp ovulation
2015/6/4
Fadrozole – a non-steroidal aromatase inhibitor was applied to common carp and goldfish to examine its ability to potentiate the stimulatory action of GnRH analogues on LH secretion in vivo. The goal ...
Intrafollicular LH administration in dairy heifers treated with a GnRH agonist
intrafollicular treatment double channel system luteinising hormone deslorelin cattle
2015/4/17
The aim of this study was to evaluate the effect of intrafollicular treatment (IFT) with different doses of luteinising hormone. Experimental heifers were treated with a single deslorelin implant to d...