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Nf1-DEFICIENT MICE DISPLAY SOCIAL LEARNING DEFICITS THAT ARE RESCUED BY THE DELETION OF PAK1 GENE
Neurofibromatosis type 1 (NF1) social learning p21-activated kinase 1 (PAK1) MAPK prefrontal cortex basolateral amygdala
2015/5/21
Neurofibromatosis type 1 (NF1) is a neurocutaneous disorder that affects roughly 1 in 3500 individuals. In addition to physical features (e.g., neurofibromas), developmental disorders are also common ...
PAK1's regulation of eosinophil migration and implications for asthmatic inflammation
airway inflammation p-21 activated kinase 1 (PAK1) chemotaxis
2015/5/21
More than 300 million people world-wide suffer from breathlessness, wheezing, chest tightness, and coughing characteristic of chronic bronchial asthma, the global incidence of which is on the rise. Al...
THE ROLE OF PAK1 IN THE CELLULAR AND MOLECULAR COMPONENTS OF PLEXIFORM NEUROFIBROMAS
Neurofibromatosis type Mast cells
2015/5/21
Neurofibromatosis type I (NF1) is a common genetic disease that affects over 200,000 patients in North America, Europe, and Japan. Individuals with NF1 display a wide variety of pathologies; important...