搜索结果: 1-15 共查到“Ref-1”相关记录19条 . 查询时间(0.082 秒)
Activation of APE/Ref-1 redox activity is mediated by reactive oxygen species and PKC phosphorylation
APE/Ref-1 reactive oxygen species redox
2014/12/12
Reactive oxygen species (ROS) arise through normal cellular aerobic respiration, and, in combination with external sources such as ionizing radiation, cigarette tar and smoke, and particulate matter g...
Role of the Multifunctional DNA Repair and Redox Signaling Protein Ape1/Ref-1 in Cancer and Endothelial Cells: Small-Molecule Inhibition of the Redox Function of Ape1
APE1/Ref-1 redox signaling cancer
2014/12/12
The DNA base excision-repair pathway is responsible for the repair of DNA damage caused by oxidation/alkylation and protects cells against the effects of endogenous and exogenous agents. Removal of th...
Prognostic role of Ape/Ref-1 subcellular expression in stage I-III breast carcinomas
DNA repair breast carcinoma immunohistochemistry
2014/12/12
The purpose of the study was to evaluate the prognostic role of the DNA repair protein APE/Ref-1 in breast carcinomas. Immunohistochemical analysis for APE/Ref-1 was performed in a series of 133 conse...
An 'environment to nucleus' signaling system operates in B lymphocytes: redox status modulates BSAP/Pax-5 activation through Ref-1 nuclear translocation
Ref-1 DNA-binding activity signaling
2014/12/12
The Ref-1 (also called APE or HAP1) protein is a bifunctional enzyme impacting on a wide variety of important cellular functions. It acts as a major member of the DNA base excision repair pathway. Mor...
Genome-wide analysis and proteomic studies reveal APE1/Ref-1 multifunctional role in mammalian cells
APE1/Ref-1 cell signaling difference analysis
2014/12/12
Apurinic apyrimidinic endonuclease/redox effector factor 1 (APE1/Ref-1) protects cells from oxidative stress by acting as a central enzyme in base excision repair pathways of DNA lesions and through i...
The Intracellular Localization of APE 1 /Ref-1: More than a Passive Phenomenon?
APE1/Ref-1 DNA repair
2014/12/12
Human apurinic/apyrimidinic endonuclease 1/redox effector factor-1 (APE1/Ref-1) is a perfect paradigm of the functional complexity of a biological macromolecule. First, it plays a crucial role, by bot...
APE1/Ref-1 Interacts with NPM1 within Nucleoli and Plays a Role in the rRNA Quality Control Process
APE1/Ref-1 NPM1 rRNA quality control
2014/12/12
APE1/Ref-1 (hereafter, APE1), a DNA repair enzyme and a transcriptional coactivator, is a vital protein in mammals. Its role in controlling cell growth and the molecular mechanisms that fine-tune its ...
Activation of APE1/Ref-1 is dependent on reactive oxygen species generated after purinergic receptor stimulation by ATP
APE1 Ref-1
2014/12/12
Apurinic apyrimidinic endonuclease redox effector factor-1 (APE1/Ref-1) is involved both in the base excision repair (BER) of DNA lesions and in the eukaryotic transcriptional regulation. APE1/Ref-1 i...
Knockdown of the DNA repair and redox signaling protein Ape1/ Ref-1 blocks ovarian cancer cell and tumor growth
base excision repair APE1/Ref-1 ovarian cancer
2014/12/12
Apurinic endonuclease 1/redox effector factor-1 (Ape1/Ref-1 or Ape1) is an essential protein with two distinct functions. It is a DNA repair enzyme in the base excision repair (BER) pathway and a redu...
APE1/Ref-1 (APE1), the mammalian ortholog of Escherichia coli Xth, and a multifunctional protein possessing both DNA repair and transcriptional regulatory activities, has a pleiotropic role in control...
RNA和输出因子结合蛋白（RNA and export factor binding proteins， REF/Aly）参与RNA的稳定、 加工和输出。本研究参照已公开的家蚕Bombyx mori aly序列（GenBank登录号： DQ497195.1）， 通过RT-PCR克隆了家蚕aly/ref基因（Bmaly/ref）。测序结果显示， 该基因的开放读码框为765 bp， 编码254个氨基酸...
法国REF防暴头盔（图）
法国奥多克·科莫迪泰克公司 防暴头盔
2009/6/18
法国奥多克·科莫迪泰克公司研制和生产的REF防暴头盔，包括REF78091式有顶饰式防暴头盔、 REF78093式无顶饰式防暴头盔和REF78101式防暴头盔面罩，主要供警察在制止骚乱时使用，可防护各种钝器打击对头部的伤害。
法国REF防弹头盔（图）
法国奥多克·科莫迪泰克公司 防弹头盔
2009/6/18
法国奥多克·科莫迪泰克公司生产的REF防弹头盔包括REF78092式防弹头盔和 REF78102式防护面罩，主要装备法国警察部队，可防护各种枪弹对头部的伤害。
法国REF系列特种警察用防弹衣（图）
法国奥多克·科莫迪泰克公司 防弹衣 警察
2009/6/18
法国奥多克·科莫迪泰克公司生产的REF系列特种警察用防弹衣包括 REF78250式和REF78251式两种产品，可有效防护各种枪弹对人体的前胸、后背和侧面的伤害，现已装备法国特种警察部队。
法国REF系列保安人员防弹衣（图）
法国奥多克·科莫迪泰克公司 防弹衣 保安人员
2009/6/18
法国奥多克·科莫迪泰克公司生产的REF系列保安人员防弹衣包括REF78501-1式、 78502-2式和78503-3式三种型号。它们是专供负责押运贵重财物的武装保安人员使用的，可有效防护各种枪弹对人体的前胸、后背和侧面的伤害。