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研究阿奇霉素联合斯奇康注射液对支气管溃疡的治愈和对髓系抑制性细胞(MDSCs MDSCs),血清免疫球蛋白E(immunoglobulin E IgE),嗜酸细胞活化活性化因子(嗜酸细胞活化趋化因子趋化因子)的影响。方法:选取2017年3月至2018年4月我院的80例支气管哮喘患者按照简单随机数表法分为观察组(42例)和对照组。 (38例),立即采用斯奇康注射液治疗,观察组在替代的基础上,采用阿奇...
支气管哮喘是最常见的过敏性疾病,它是多种细胞参与的慢性气道炎症。酸性哺乳动物壳多糖酶(acid mammals chitinase,AMCase)作为壳多糖酶家族重要成员之一,与其下游信号分子嗜酸性粒细胞趋化因子-3一起,通过依赖白细胞介素13诱导的Th2炎症途径而发挥作用,近年来已成为哮喘研究中的热点。
Eotaxin-induced expression of membrane type 1 matrix metalloproteinase mRNA in human eosinophils
basement membrane degradation eosinophil eotaxin matrix metalloproteinase-2 matrix metalloproteinase-9 membrane-type matrix metalloproteinase
2010/11/25
Eosinophil penetration across the basement membrane (BM) is thought to be dependent on the degradation of membrane components. In this process, matrix metalloproteinases (MMP) appear to be primarily r...
Inhalant corticosteroids inhibit mechanical strain-induced RANTES and eotaxin production by human airway smooth muscle cells
airway smooth muscle cells eotaxin inhaled corticosteroids mechanical strain RANTES
2010/11/24
The results showed that: (i) mechanical strain, including stretch and compression, stimulated ASM cells to produce RANTES and eotaxin; and (ii) FP and BUD inhibited mechanical strain-induced and TNF-α...
Mechanisms involved in human eosinophil chemotaxis induced by the newly cloned C-C chemokine eotaxin
calcium chemotaxis eosinophil eotaxin signaling
2010/11/29
The present study was performed in order to investigate the mechanism(s) involved in eotaxin-induced normal human eosinophil chemotaxis using a 48-well microchemotaxis chamber assay. Eotaxin, at a wid...