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A plant-based, oral delivery of insulin regulates blood sugar levels similar to natural insulin（图）
Research Dental Medicine 天然胰岛素
2023/6/27
Insulin production has, for the last 50 or so years, come with some risks to the patient. Even so, the medication is lifesaving for the estimated 537 million adults living with diabetes worldwide, wit...
Only one human fat cell subtype responds to insulin stimulation
AdipoPLIN fat cells insulin diabetes
2021/8/11
It is well known that fat cells can influence our sensitivity to insulin. Now, researchers have discovered that there are three different subtypes of mature fat cells in white adipose tissue and that ...
Plasma glucose and insulin responses after consumption of breakfasts with different sources of soluble fiber in type 2 diabetes patients: a randomized crossover clinical trial
dietary fiber plasma glucose plasma insulin postprandial period soluble fiber type 2 diabetes
2018/11/20
Background: The amount and quality of carbohydrates are important determinants of plasma glucose after meals. Regarding fiber content, it is unclear whether the intake of soluble fibers from foods or ...
Effect of the interaction between diet composition and the PPM1K genetic variant on insulin resistance and β cell function markers during weight loss: results from the Nutrient Gene Interactions in Human Obesity: implications for dietary guidelines (NUGENOB) randomized trial
gene-diet interaction glucose concentrations NUGENOB obesity weight loss
2018/11/19
Background: Circulating branched-chain amino acids (BCAAs) and aromatic amino acids (AAAs) have been shown to be associated with insulin resistance and diabetes risk. The common rs1440581 T allele in ...
Effect of the interaction between diet composition and the PPM1K genetic variant on insulin resistance and β cell function markers during weight loss: results from the Nutrient Gene Interactions in Human Obesity: implications for dietary guidelines (NUGENOB) randomized trial
gene-diet interaction glucose concentrations NUGENOB obesity weight loss
2018/11/16
Background: Circulating branched-chain amino acids (BCAAs) and aromatic amino acids (AAAs) have been shown to be associated with insulin resistance and diabetes risk. The common rs1440581 T allele in ...
The effect of magnesium supplementation on blood pressure in individuals with insulin resistance, prediabetes, or noncommunicable chronic diseases: a meta-analysis of randomized controlled trials
blood pressure cardiovascular diseases insulin resistance
2018/11/19
Background: To our knowledge, the effect of magnesium supplementation on blood pressure (BP) in individuals with preclinical or noncommunicable diseases has not been previously investigated in a meta-...
The effect of magnesium supplementation on blood pressure in individuals with insulin resistance, prediabetes, or noncommunicable chronic diseases: a meta-analysis of randomized controlled trials
blood pressure cardiovascular diseases insulin resistance
2018/11/16
Background: To our knowledge, the effect of magnesium supplementation on blood pressure (BP) in individuals with preclinical or noncommunicable diseases has not been previously investigated in a meta-...
Pretreatment fasting plasma glucose and insulin modify dietary weight loss success: results from 3 randomized clinical trials
glucose insulin precision medicine personalized nutrition weight glycemic load glycemic index fiber prediabetes diabetes
2018/11/15
Background: Which diet is optimal for weight loss and maintenance remains controversial and implies that no diet fits all patients.
Chronic fructose substitution for glucose or sucrose in food or beverages has little effect on fasting blood glucose, insulin, or triglycerides: a systematic review and meta-analysis
sugar replacement fructose glucose sucrose insulin triglycerides diabetes body weight
2018/11/15
Background: Conflicting evidence exists on the role of long-term fructose consumption on health. No systematic review has addressed the effect of isoenergetic fructose replacement of other sugars and ...
Fructose replacement of glucose or sucrose in food or beverages lowers postprandial glucose and insulin without raising triglycerides: a systematic review and meta-analysis
sugar replacement, fructose, glucose, sucrose, insulin, triglycerides, diabetes, body weight
2018/11/15
Background: Conflicting evidence exists on the effects of fructose consumption in people with type 1 and type 2 diabetes mellitus. No systematic review has addressed the effect of isoenergetic fructos...
Vitamin D supplementation has no effect on insulin sensitivity or secretion in vitamin D–deficient, overweight or obese adults: a randomized placebo-controlled trial
insulin secretion insulin sensitivity obesity random-ized trial RCT, vitamin D
2018/11/14
Background: Vitamin D supplementation has been proposed as a potential strategy to prevent type 2 diabetes. Existing clinical trials have been limited by short duration, low doses of vitamin D, variab...
Inhibition of sweet chemosensory receptors alters insulin responses during glucose ingestion in healthy adults: a randomized crossover interventional study
sweet taste receptors lactisole glucose intolerance insulin saccharin artificial sweeteners OGTT modeling analysis
2018/11/13
Background: Glucose is a natural ligand for sweet taste receptors (STRs) that are expressed on the tongue and in the gastrointestinal tract. Whether STRs directly contribute to the regulation of gluco...
2017年IGF和胰岛素系统的生理学和疾病戈登学术会议（The Gordon Research Conference (GRC) on IGF & Insulin System in Physiology & Disease）
Physiology Disease
2017/1/19
The 2017 Gordon Conference on the Insulin-Like Growth Factor (IGF) and Insulin System in Physiology and Disease will present cutting-edge research on the roles of IGFs and insulin and their signaling ...
Alterations in human milk leptin and insulin are associated with early changes in the infant intestinal microbiome
milk leptin insulin the infant intestinal microbiome
2018/11/12
We read with great interest the study by Lemas et al. (1) that reported early changes in the gut microbiota composition and functions of exclusively breastfed infants born from obese mothers compared ...