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Background: Telomere length and telomere shortening are associated with age-related health outcomes. Only a few studies have been able to longitudinally report on factors that are associated with chan...
Determining the sulfur amino acid (SAA) requirements of humans has remained elusive because of the complex nature of SAA metabolism. Current recommendations are based on nitrogen balance studies.
The currently accepted total aromatic amino acid requirement for adults is based on nitrogen balance measurements in individuals who received their intake of aromatic amino acids solely as phenylal...
Treatment of phenylketonuria (PKU) consists of restriction of natural protein and provision of a protein substitute that lacks phenylalanine but is enriched in tyrosine. Large and unexplained diffe...
Th e defensive reaction of apple cultivar Idared (Malus domestica Borkh.) was studied after inoculation with three diff erent pathogens (Penicillium expansum, Monilinia fructigena, and Gloeospor...
Part of the PSPAL1 gene (corresponding to the proximal promoter, exon 1 and intron) from eight pea varieties was sequenced and compared to the published sequence of PSPAL1 gene from Midoriusui cultiva...
Phenylketonuria (PKU) is a metabolic disease in which the untreated patients can show irreversible mental retardation and the use of milk by phenylketonurics patients is forbidden. With the aim of pre...
This study was conducted to evaluate the efficacy of the dipeptide form of phenylalanine as a new source of amino acid in terms of growth performance and whole-body amino acid composition in compariso...
We studied the relationship between the increase in resistance to Pythium snow rot provided by cold acclimation and changes in phenylalanine ammonia-lyase (PAL) activity, and the contents of total ph...
This study involves the preparation of whey hydrolysates with low phenylalanine (Phe) content aiming the treatment of phenylketonuria. For hydrolysing the proteins, two enzymes were used, papain and p...
With the aim of producing dietary supplements for phenylketonurics, using whey hydrolysates as protein sources, the effect of some procedures over phenylalanine (Phe) removal was evaluated. Twelve whe...
Two rapeseed (Brassica napus L.) phenylalanine ammonia-lyase 2 genes (BnPAL2-1 and BnPAL2-2) were isolated. The full-length cDNAs of BnPAL2-1 and BnPAL2-2 are 2422 bp and 2421 bp, with corresponding g...
The contribution to casein biosynthesis of peptides derived from blood was examined in late lactation goats (254 to 295 d in milk). Ratios of mammary uptake of free amino acids (AA) in blood to output...
为探讨中国苯丙酮尿症(PKU)人群中苯丙氨酸羟化酶(PAH)基因外显子7的突变特征,对147例PKU患儿的294个PAH基因外显子7以及两侧部分内含子序列,应用PCR-单链构象多态性(SSCP)分析及基因序列分析的方法进行了筛查和确定。共发现13种突变基因:G239D、R241C、R241fs、R243Q、G247S、G247V、R252Q、L255S、R261Q、M276K、E280G、P281...

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