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Receptor-like kinases sustain symbiotic scrutiny
receptor-like kinases (RLKs) symbiotic scrutiny mycorrhizal fungi nitrogen-fixing bacteria
2024/1/22
Plant receptor-like kinases (RLKs) control the initiation, development and maintenance of symbioses with beneficial mycorrhizal fungi and nitrogen-fixing bacteria. Carbohydrate perception activates sy...
Chemical control of receptor kinase signaling by rapamycin-induced dimerization
leucine-rich repeat receptor kinase brassinosteroids BRI1 BAK1 FLS2
2023/12/7
Membrane-localized leucine-rich repeat receptor kinases (LRR-RKs) sense diverse extracellular signals, and coordinate and specify cellular functions in plants. However, functional understanding and id...
Insights into a receptor that lets insects sense scents(图)
odor receptors olfactory system Mh OR5 Orco
2021/8/9
In insects, odorant receptor proteins form membrane ion channels that open on binding to an odorant molecule. The structures of an inactive and an active channel lend insights into how insects detect ...
A human neutralizing antibody targets the receptor binding site of SARS-CoV-2
Preventive medicine SARS-CoV-2 Viral infection
2020/6/11
An outbreak of the coronavirus disease 2019 (COVID-19)1–3, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)4 spread globally. Countermeasures are needed to treat and prevent ...
Key Residues of the Receptor Binding Motif in the Spike Protein of SARS-CoV-2 That Interact With ACE2 and Neutralizing Antibodies
SARS-CoV-2 cross-neutralizing antibody receptor binding motif spike protein substitution mutation
2020/6/11
Coronavirus disease 2019 (COVID-19), caused by the novel human coronavirus SARS-CoV-2, is currently a major threat to public health worldwide. The viral spike protein binds the host receptor angiotens...
RBR-type E3 ligases and the Ub-conjugating enzyme UBC26 regulate ABA receptor levels and signaling
ABA receptor RFA PYL4 Arabidopsis 26S proteasome
2024/2/27
The turnover of abscisic acid (ABA) signaling core components modulates the plant's response to ABA and is regulated by ubiquitination. We show that Arabidopsis (Arabidopsis thaliana) RING finger ABA-...
Adjusting soluble transferrin receptor concentrations for inflammation: Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA) project
anemia inflammation iron deficiency nutritional assessment soluble transferrin receptor
2018/11/15
Background: Iron deficiency is thought to be one of the most prevalent micronutrient deficiencies globally, but an accurate assessment in populations who are frequently exposed to infections is impede...
Allelic variation of melanocortin-1 receptor locus in Saudi indigenous sheep exhibiting different color coats
MC1R Ovis aries SNPs Saudi Sheep
2017/3/8
This study was designed to characterize the DNA polymorphisms of the melanocortin-1 receptor (MC1R) gene in indigenous Saudi Arabian sheep breeds exhibiting different color coats, along with individua...
Peroxisome proliferator activated receptor ligands affect porcine endometrial steroids production during the estrous cycle and early pregnancy:an in vitro study
PPAR progesterone estradiol luteal phase periimplantation
2016/9/1
In the present study, we investigated the effect of PPAR ligands on progesterone (P4) and 17β-estradiol (E2) secretion, as well as 3β-hydroxysteroid dehydrogenase/Δ(5)-Δ(4) isomerase (3β-HSD) mRNA exp...
Production of Transgenic Pigs with an Introduced Missense Mutation of the Bone Morphogenetic Protein Receptor Type IB Gene Related to Prolificacy
Transgenic Handmade Cloning Pig BMPR1B Coding Sequence Reproductive Traits
2016/7/27
In the last few decades, transgenic animal technology has witnessed an increasingly wide application in animal breeding. Reproductive traits are economically important to the pig industry. It has been...
Serum transferrin receptor concentration indicates increased erythropoiesis in Kenyan children with asymptomatic malaria
Iron deficiency anemia ferritin
2016/6/14
Serum transferrin receptor concentrations indicate
both erythropoietic activity and the deficit of functional iron in
the erythron. In contrast with serum ferritin concentrations,
serum transferrin...
Caffeine intake increases the rate of bone loss in elderly women and interacts with vitamin D receptor genotypes
bone mineral density elderly women Caffeine
2016/6/14
Our goals were 1) to compare in both a crosssectional
study and a 3-y longitudinal study the bone mineral
density (BMD) of postmenopausal women consuming high or
low amounts of caffeine and 2) to s...
Receptor-mediated signaling pathways: potential targets of modulation by dietary fatty acids
dietary fat tyrosine kinase protein kinase
2016/6/1
Extracellular signals are transmitted to intracellular
targets through many signal-transduction pathways. Each
signaling pathway is composed of a network of interacting signaling
molecules that reg...