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Evolution of Hybrid Incompatibilities in Gene Regulatory Networks
antagonistic coevolution cis-trans coevolution compensatory evolution parasitism pleiotropy speciation
2014/12/18
Under the Dobzhansky-Muller model, postzygotic isolation results from incompatibility between interacting genes. Evidence points to regulatory networks as a rich source of incompatibilities that impac...
Type-dependent irreversible stochastic spin models for gene regulatory networks
Stochastic spin model gene regulatory network biochemical pathway repressilator
2010/11/25
There are many different mathematical setups to model the dynamics of gene regulatory networks (GRNs),most based on Boolean networks or chemical kinetics ideas. Here we present an approach to model GR...
Application of new probabilistic graphical models in the genetic regulatory networks studies
Application probabilistic graphical models genetic regulatory networks studies
2010/11/15
This paper introduces two new probabilistic graphical models for reconstruction of genetic regulatory networks using DNA microarray data. One is an Independence Graph (IG) model with either a forward ...
A systematic framework for the synthesis and analysis of regulatory networks
A systematic framework regulatory networks
2009/12/24
A systematic framework for the synthesis and analysis of regulatory networks.
A Mixed Integer Optimization Algorithm to Reverse Engineer Transcriptional Regulatory Networks
mixed-integer optimization gene regulation Engineer Transcriptional Regulatory Networks
2009/12/24
A major goal in post-genomic era is to reverse engineer transcriptional regulatory networks. Advances in high-throughout technologies e.g. DNA microarrays coupled with the working knowledge on the con...
Microdynamics and Criticality of Adaptive Regulatory Networks
Microdynamics Adaptive Regulatory Networks
2010/4/7
We present a model of adaptive regulatory networks consisting of a simple biologically-motivated rewiring procedure coupled to an elementary stability criterion. The resulting networks exhibit a chara...
Informative Gene Selection and Design of Regulatory Networks Using Integer Optimization
Informative Gene Selection and Design Regulatory Networks Integer Optimization
2009/12/24
Informative Gene Selection and Design of Regulatory Networks Using Integer Optimization.