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In 1796, English physician Edward Jenner decided to investigate a tale he had often heard — that milkmaids infected with cowpox became immune to smallpox, a much more dangerous affliction. To test thi...
Aim: To determine the effects of smoking on vascular endothelial growth factor (VEGF) expression and apoptosis in lens and corneal epithelial cells. Materials and methods: This experimental study incl...
Cells in the musculoskeletal system can respond to mechanical stimuli, supporting tissue homeostasis and remodeling. Recent studies have suggested that mechanical stimulation also influences the di...
An endothelial cell (EC) smooth muscle cell (SMC) co-culture model of the arterial wall was used to study the effect of fluid shear stress on EC behavior. This model, in addition to being a more rea...
The mechanism by which lead may cause a perturbotion in the nevous system is through the nitric oxide synthase. In this study the effect of lead acetate on the hippocampal constitutive nitric oxide pr...
The glomerular mesangial cells (GMC) play a central role in the synthesis and turnover of the glomerular mesangial matrix. The breakdown of the matrix likely depends on the balance between of a variet...
Altered functions of mesangial cells induced by high glucose concentrations are thought to play an important role in the pathogenesis of diabetic nephropathy. We therefore investigated the effect of h...
Based on the evaluation of two human cell lines, Hela and Chang, abeuploidy and several marker chromosomes were found in both cells. The morphological characteristic of marker chromosomes of Chang cel...
Based on the evaluation of two human cell lines, Hela and Chang, abeuploidy and several marker chromosomes were found in both cells. The morphological characteristic of marker chromosomes of Chang cel...
The immune responses that develop following Epstien-Barr Virus (EBV) infection are complex and involve both humoral and to a greater extent cell-mediated immune mechanisms. To evaluate the immune resp...
Multiresolution identification of germ layer components in teratomas derived from human, nonhuman primate, and murine embryonic stem cells.
Fluorescence microscope images capture information from an entire field of view, which often comprises several cells scattered on the slide. We have previously trained classifiers to accurately pre...
A Neural Network Classifier Capable of Recognizing the Patterns of all Major Subcellular Structures in Fluorescence Microscope Images of HeLa Cells.
Bafilomycin A1 (baf), a specific inhibitor of vacuolar proton ATPases, is commonly employed to demonstratethe requirement of low endosomal pH for viral uncoating. However, in certain cell types baf al...

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