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Adverse neurological manifestations of exposure to high hydrostatic pressure include tremor and convulsions, suggesting an alteration in synaptic transmission, particularly with inhibitory pathways. B...
We have investigated the effects on cultured cells of high pressure separately and combined with vanadate. Growth of Chinese hamster ovary cells was reduced at pressure above 75 bar; the reduction was...
Hydrostatic compression to 15 MPa caused a drop in spontaneous beating frequency (BF) of isolated rat atria kept in tris solution at 37 degrees C by 30.6 +/- 7.2%. Introduction of superfusing solution...
This investigation was intended to a) establish a relationship between pressure and thickness (and hence insulation) of wetsuits during acute changes in pressure from 0.5 to 5 atmospheres absolute (AT...
The aim of this study was to determine whether administration of ethanol protects rats against the preconvulsive symptoms of high pressure nervous syndrome (HPNS). Male Sprague-Dawley rats were given ...
Upright immersion induces respiratory mechanical changes that may impair pulmonary function during hyperbaric exercise. To evaluate this, 10 divers performed an incremental cycling protocol while imme...
We investigated the effect of negative pressure breathing during the inspiratory phase only (intermittent NPB) in 9 healthy male subjects who were in a sitting position and had no food or fluid intake...
Saturation of a liquid with gas before perfusing a tissue or cellular preparation under pressure can be achieved by bubbling the gas through the liquid. A container for this purpose that is housed in ...
Exposure to environmental pressures in excess of 20 atm abs can precipitate a hyperexcitability state known as high pressure neurologic syndrome (HPNS). Little is known about the underlying neurochemi...
High pressure induces hyperexcitability and convulsions in both intact and decerebrated animals. However, pressure suppresses synaptic transmission in isolated invertebrate preparations. We examined t...
We have measured in 7 divers forced vital capacity (FVC), forced expired volume in 1 s (FEV1), and forced midexpiratory flow rate (FEF25-75%) before and after exposure to dry or humid breathing gas of...
This study reports results from experiments designed to test common, clinically useful anti-convulsants for their effectiveness, if any, against the high pressure nervous syndrome (HPNS) in rats. Phen...
The KF/SQI-fusion method described in this article was shown to provide an accurate estimate of blood pressure and HR derived from the ABP waveform even in the presence of high levels of persistent no...
Hypervolemia is supposed to be the principal factor in hypertension in chronic hemodialysis adults. In this study, the role of intensive ultrafiltration (UF) treatment to reduce hypertension due to hy...
In the present study, we aimed to investigate the effects of dietary salt restriction and loading on extracellular fluid volume (ECFV), blood pressure (BP), heart rate (HR), glomerular filtration rate...

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