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Plasma leptin in humans is subject to both longand short-term regulation; it correlates with indexes of body fat that can only change slowly. However, short-term fasting causes large and rapid decr...
The positive association between body weight and bone mineral density (BMD) is well documented; in contrast, the effect of changes in body weight on BMD is not well understood, particularly, in nor...
It has been suggested that vitamin E can counteract the age-associated decline in cellular immune responsiveness (CIR). Particularly, T helper cell type 1 (Th1) activity, ie, interferon (IFN) g–pro...
The absorption efficiency of calcium in humans is low. Some studies in infants have shown that calcium absorption can be increased by adding medium-chain triacylglycerols to the formula diet.
Infections due to Candida albicans occur readily in situations in which ample glucose is available. In mice, dietary refined carbohydrate supplementation leads to higher rates of Candida growth in ...
Cirrhosis is considered to be a catabolic disease associated with a high prevalence of protein-energy malnutrition (1). Increased energy expenditure (EE) has been proposed (1) and editorialized (2) to...
Nondigestible oligosaccharides have been claimed to benefit the health of the colon by selectively stimulating the growth of bifidobacteria and by decreasing the toxicity of the colon contents
Vegetarians have lower platelet and plasma concentrations of n23 polyunsaturated fatty acids (PUFAs) than do omnivores. We recently showed that male vegetarians have higher platelet aggregability t...
Diets with a low glycemic index (GI) have been shown to improve glucose tolerance in both healthy and diabetic subjects. Two potential mechanisms are discussed in relation to long-term metabolic ef...
Deficiencies of iron, iodine, and vitamin A are prevalent worldwide and can affect the mental development and learning ability of schoolchildren.
Tocotrienols, lipid-soluble antioxidants with vitamin E activity, have been reported to lower LDL-cholesterol concentrations and platelet aggregation in men, but results are contradictory.
Epidemiologic studies have shown alcohol consumption to be inversely as well as positively related to body weight and body fat. Metabolic studies have shown an increase in energy intake as well as ...
Epidemiologic studies suggest that foods rich in flavonoids might reduce the risk of cardiovascular disease.
Micronutrient deficiencies remain common in preschool children in developing countries. Interventions focus on single micronutrients and often lack effectiveness. Weekly instead of daily supplement...

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