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HIV-complicated meningovascular syphilis: Atypical symptoms with promising result using low molecular weight heparin
Meningovascular Syphilis HIV
2013/2/20
Both WHO and the CDC of Taiwan have reports indicating a dramatic increase in incidence of both syphilis and HIV. With their co-infection, neurosyphilis will become a major issue, and meningovascular ...
Clinical and Molecular Aspects of Sjogren-Larsson Syndrome Reported in an Iranian Consanguineous Family with Triplet Affected Individuals
Sjogren-Larsson Skin disease Mutation Iran
2015/9/25
Background: Sjogren Larsson Syndrome (SLS; OMIM: 270200) is an autosomal recessive neuro-cutaneous disorder characterized by mental retardation, congenital ichthyosis and spastic paraplegia. SLS is ca...
Molecular Mechanisms of FLT3-ITD-Induced Leukemogenesis
Acute myeloid leukemia Blood -- Diseases
2015/5/21
Internal tandem duplications in FMS-like receptor tyrosine kinase (FLT3-ITDs) are seen in approximately 25% of all acute myeloid leukemia (AML) patients. FLT3-ITDs induce FLT3 ligand (FL)-independent ...
The University of Queensland and Axiom Molecular accelerate radiopharmaceutical research
radiopharmaceutical research
2014/7/17
A strategic alliance between The Centre for Advanced Imaging (CAI) at The University of Queensland (UQ) and Axiom Molecular Pty Ltd is set to boost radiopharmaceutical research, development and commer...
Molecular Characterization of Fasciola hepatica Isolates by RAPD-PCR and Ribosomal ITS1 Sequencing
Fasciola hepatica RAPD-PCR Ruminant Iran
2015/9/22
Background: Understanding genetic structure and status of genetic variation of the Fasciola hepatica populations has important implications for epidemiology and effective control of fasciolosis. The a...
Evaluation of the Efficacy of Aspirin and Low Molecular Weight Heparin in Patients with Unexplained Recurrent Spontaneous Abortions
Recurrent abortions Thromboprophylaxis Aspirin Heparin
2015/9/21
Background: The roles of inflammatory cytokines and local placental thrombosis in patients with unexplained recurrent spontaneous abortion (URSA) have been shown. Since low molecular weight heparin (L...
Role of molecular markers in breast cancer therapy
Breast neoplasms Therapy Prognostication Prediction
2012/7/13
Translational research, in general, means to take knowledge from one area into a second. Traditional thought to represent transfer of knowledge from basic research into the clinic, translational resea...
Nature Structural & Molecular Biology发表中国科学院生物物理研究所肉碱膜转运蛋白CaiT三维结构研究成果(图)
Nature Structural & Molecular Biology 膜转运蛋白CaiT
2010/4/1
2010年3月28日,生物物理研究所江涛研究员课题组在 Nature Structural & Molecular Biology杂志在线发表了题为“Crystal Structure of the Carnitine Transporter and Insights into the Antiport Mechanism ”的文章。该研究解析了肉碱膜转运蛋白CaiT的三维结构,并对其分子机制进行...
Nanoparticle’s Size Effect on Its Translocation Across a Lipid Bilayer: A Molecular Dynamics Simulation
Size Nanoparticle Molecular Dynamics Lipid Bilayer
2010/7/16
Understanding the interaction between nanoparticles (NPs) and cell membranes (dipalmitoylphosphatidylcholine or DPPC bilayers) is important for the design of drug delivery systems and provides insight...
Molecular typing of methicillin-resistant Staphylococcus aureus isolated from bloodstream infections in a university hospital
Methicillin-resistant Staphyococcus aureus bloodstream infections AP-PCR PFGE
2010/1/11
Aim: Bloodstream infections due to methicillin-resistant Staphyococcus aureus (MRSA) strains are one of the major problems in many hospitals. Molecular typing provides very useful information about th...
Molecular Detection of Prostate Specific Antigen in Patients with Prostate Cancer or Benign Prostate Hyperplasia the First Investigation from Iran
PSA BPH Prostate cancer
2009/12/30
Prostate cancer is the second common form of cancer in men. Detection of circulating Prostate Specific Antigen (PSA) transcripts has effectively been used for early diagnosis of prostate cancer cells....
Molecular Characterization of Toxoplasma gondii from Bird Hosts
Bird hosts Gallus domesticus Anas sp
2009/12/29
The determination of Toxoplasma gondii prevalence in a variety of domestic birds is thought as a good indicator of distribution of T.gondii ooccyts in the environment. To verify the potential role of ...
Molecular Characterization of Toxoplasma gondii from Bird Hosts
Bird hosts Gallus domesticus Anas sp
2009/12/29
The determination of Toxoplasma gondii prevalence in a variety of domestic birds is thought as a good indicator of distribution of T.gondii ooccyts in the environment. To verify the potential role of ...
MOLECULAR MODELLING OF HUMAN ALDEHYDE OXIDASE AND IDENTIFICATION OF THE KEY INTERACTIONS IN THE ENZYME-SUBSTRATE COMPLEX
Aldehyde oxidase Molecular modeling 3D-QSAR genetic algorithm
2009/12/25
Aldehyde oxidase (EC 1.2.3.1), a cytosolic enzyme containing FAD, molybdenum and iron-sulphur cluster, is a member of non-cytochrome P-450 enzymes called molybdenum hydroxylases which is involved in t...
Molecular Mechanisms Regulating mRNA Stability: Physiological and Pathological Significance
mRNA stability AU-rich elements AU-binding proteins RNA interference microRNA computational biology
2009/12/24
The cytoplasmic level of a messenger RNA, and hence protein, depends not only upon its rates of synthesis,processing, and transport, but its decay rate as well. mRNA decay rates are frequently not sta...