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Combined influence of temperature and hydrostatic pressure on cardiac conduction
cardiac temperature hydrostatic animal dog rabbit
2009/7/17
Interactions of temperature and hydrostatic pressure were examined in three types of cardiac tissue. Decreases in temperature from 37 degrees C to 27 degrees C and increases in pressure from 1 to 150 ...
Effect of high ambient pressure and oxygen tension on organ blood flow in the anesthetized rat
perfusion oxygen animal rat
2009/7/16
Cardiac output (CO) and blood flow to major organs were investigated in pentobarbital-anesthetized rats using 85Sr- and 141Ce-labeled microspheres (MS) (15 +/- 1 microns (SD)) injected into the left v...
Ventilatory and occlusion-pressure responses to hypercapnia in divers and non-divers
pulmonary human divers non-divers
2009/7/16
Ventilatory (VE/PCO2) and occlusion-pressure (P0.1/PCO2) responses to progressive hypercapnia (rebreathing method of Read (1)) were estimated in 20 normal subjects and 22 scuba divers. Indexes of CO2 ...
Spontaneous activity of rat portal vein at normal and elevated hydrostatic pressure
portal vein hyperbaric animal rat
2009/7/16
The effects of high hydrostatic pressure on the spontaneous contractile activity of isolated rat portal veins were studied. During compression, an increase of activity was seen, whereas stable elevate...
A system for pharmacological studies in small animals at high pressure
pharmacological animal rat
2009/7/16
A four-liter pressure chamber was constructed for pharmacological experiments in rats; it consisted of the following: 1) a system for repeated, accurate injection; 2) an alternative single-dose inject...
Interactions of thiopentone,light mineral oil,and pressure at frog sciatic nerve
decompression sciatic nerve frog animal thiopentone
2009/7/16
Combinations of thiopentone, light mineral oil, and pressure to as much as 160 ATA were applied to the isolated, thermostated (18 degrees C) frog sciatic nerve. Amplitude and rise rate of the compound...
Method for separation of cells and suspending medium at high pressure
human high pressure Method erythrocytes
2009/7/16
We describe a pressure chamber designed for measuring fluxes and equilibrium distributions of substances between cells in suspension and the extracellular medium at pressures up to 400 ATA. The pressu...
Hyperbaric chamber for evaluating hydrostatic pressure effects on tissues and cells
human chamber pressure effects tissues
2009/7/16
A chamber system is described for the study of pure hydrostatic pressure effects on tissues and cells. The small chamber has an internal volume of 7.6 liters and is rated for working pressures up to 4...
Pressure equilibration of the middle ear during ascent
human ear barotrauma equalization ascent
2009/7/16
The capacity to equilibrate the middle ear with the ambient pressure depends on different factors. During descent when the clearing is active the technique is the most important factor. During ascent ...
Muscle preparations from rat atria were hydraulically compressed in circulating Tris-buffered solution kept at 37 degrees C. Spontaneously beating preparations decreased their beating frequency with 3...
Hydrostatic pressure reduces synaptic efficiency by inhibiting transmitter release
drug pressure transmitter release
2009/7/16
The amplitude of post-synaptic potentials at an identified synapse in the Aplysia central nervous system can be modulated by the application of hydrostatic pressure. Postsynaptically controlled functi...
Pharmacological evidence for multiple sites of action of pressure in mice
high pressure nervous syndrome animal mice drug heliox
2009/7/16
The ability of eight diverse pharmacological agents to ameliorate the high pressure nervous syndrome (HPNS) in mice was studied. Data were obtained for the end points: coarse tremors, complete spasms,...
Effect of high pressure on EEG burst suppression dose of thiopental in rats
drug thiopental animal rat Electroencephalography heliox
2009/7/16
The anesthetic induction dose of thiopental in rats was studied at 1 ATA air, 1 ATA helium-oxygen (He-O2), 4 ATA air, and at 4 ATA air plus 67 ATA helium (71 ATA). The compression rate was 0.3 ATA/min...
Patterns of interaction of effects of light metabolically inert gases with those of hydrostatic pressure as such--a review
decompression human animal mice
2009/7/16
This review of available literature attempts to interpret net effects of metabolically inert light gases (He, H2, and Ne) as the resultant of hydrostatic pressure and intrinsic pharmacological effects...
Combined effect of beating rate and hydrostatic pressure on excitation in cardiac muscle
cardiac heart rate hydrostatic animal dog
2009/7/16
Canine cardiac Purkinje fibers stimulated at frequencies from 1-4 Hz were exposed to hydrostatic pressures of 1 and 150 ATA. Both increases in stimulation frequency and pressure slowed conduction and ...