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Positive-pressure oxygen breathing and pulmonary atelectasis during immersion
human oxygen pulmonary atelectasis immersion
2009/7/16
The effect on vital capacity of 1 h of oxygen breathing with and without continuous positive pressure was studied in five subjects during immersion. Vital capacity (VC) was used as an index of pulmona...
Effect of high ambient pressure and oxygen tension on organ blood flow in conscious trained rats
cardiac output rat animal Blood Circulation
2009/7/15
Cardiac output and blood flow to different organs and tissues were investigated in conscious trained rats using radiolabeled microspheres (MS) injected into the left ventricle. Two subsequent MS injec...
Pressure in the treatment of spinal cord decompression sickness
decompression sickness spinal cord animal dog
2009/7/15
Previous work had shown that a Po2 of about 2.0 bar was the optimal Po2 for the treatment of spinal cord decompression sickness (DCS). With 20 anesthetized dogs the hypothesis was tested that pressure...
Failure of naloxone or beta-endorphin to affect pressure-induced tremor in guinea pig
naloxone beta-endorphin HPNS syndrome
2009/7/15
Naloxone in doses up to 2 mg/kg and beta-endorphin in doses up to 1 mg/kg had no suppressive effect on pressure-induced tremor or cortical EEG activity in the guinea pig. The lack of effect of either ...
Failure of naloxone or beta-endorphin to affect pressure-induced tremor in guinea pig
tremor guinea pig naloxone beta-endorphin
2009/7/15
Naloxone in doses up to 2 mg/kg and beta-endorphin in doses up to 1 mg/kg had no suppressive effect on pressure-induced tremor or cortical EEG activity in the guinea pig. The lack of effect of either ...
Gas inertia and ventilatory measurements under pressure: methodological considerations
equipment human spirometer bag-in-box apparatus method
2009/7/15
A bag-in-box apparatus with a spirometer was used to measure the ventilatory minute volume in subjects exercising at air pressures up to 6.8 atm. During rest there was good agreement between minute vo...
Reversal of pressure-induced tremors in rats by step decompression and by inert gases
decompression animal mice
2009/7/15
A method for continuously recording the motor activity of pressurized rats was used to monitor their condition after 1) holding pressure constant after compression, 2) decompression, and 3) adding nit...
Effect of high hydrostatic pressure on sodium transport across toad skin
sodium transport toad skin animal Bufo marinus
2009/7/15
The short-circuit current (Isc) was measured as an index of active net sodium transport across the isolated toad skin under various hydrostatic pressures up to 300 ATA. Upon compression, the base-line...
Cerebral arterial air embolism:III.Cerebral blood flow after decompression from various pressure treatments
cortical evoked potentials Cerebral arterial air embolism Cerebral blood flow
2009/7/15
The effect of various combinations of time between 2 and 20 min and between pressures of 2.8 and 10 bar (60 and 300 ft) breathing air or oxygen at 2.8 bar (60 ft), on the continued recovery of cortica...
Cerebral arterial air embolism: II. Effect of pressure and time on cortical evoked potential recovery
submarine human Cerebral arterial air embolism cortical evoked potentials animal dog
2009/7/15
In a dog model of cerebral arterial gas embolism we studied the relative merits of several different treatments: air breathing at 2.8, 6, 8, and 10 bar (60, 165, 230, and 300 ft), and oxygen breathing...
Effects of halothane and hydrostatic pressure on sodium channels in squid axon
neurological squid animal halothane high pressure nervous syndrome
2009/7/14
The effects of halothane and hydrostatic compression have been studied on the voltage-dependent sodium conductances in the squid giant axon. Compression to 150 atmospheres reduced the time course of b...
Effects of high pressure on the release of excitatory amino acids by brain synaptosomes
decompression neurological
2009/7/14
Excitatory amino acid antagonists have been shown to protect against the hyperexcitability associated with exposure to high pressure. This suggests that these excitatory neurotransmitter substances ma...
Ionic basis of short-circuit current in toad skin at high hydrostatic pressure
Membrane Potentials toad skin animal Bufo marinus
2009/7/14
The toad skin and urinary bladder are widely used for the study of water and Na+ transport under high pressure. These tissues can be mounted in Ussing type chambers and ion transport can be measured b...
Pressure and temperature modulation of conduction in a bifurcating axon
bifurcating axon Neural Conduction pressure thermal animal crustacean
2009/7/14
A bifurcating crustacean motor neuron, which serves an integrative function by selectively controlling output to its daughter branches, was examined for its behavioral response to changes in pressure ...
Effect of pressure on oxidative metabolism of drugs by mouse hepatic microsomes
animal mice oxidative metabolism hepatic microsomes delta-9-tetrahydrocannabinol Cannabis drug
2009/7/14
The metabolism of antipyrene and delta-9-tetrahydrocannabinol (delta-9-THC) was studied in vitro with mouse liver supernatant and 105,000 g microsomes at 450 atm pressure. No significant change in rat...