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Researchers at the University of Illinois report they can alter blood cell development through the use of biomaterials designed to mimic characteristics of the bone marrow.The findings, reported in th...
We are pleased to announce the 12th meeting on Cell Death, to be held at Cold Spring Harbor Laboratory from Tuesday evening, August 15, until after lunch on Saturday, August 19, 2017. The meeting will...
The meeting will focus on the basic biology of stem cells and the dynamic interactions between stem cells and their microenvironment or niche. Topics will include the mechanisms controlling stem cell ...
Directed cell migration is a spectacular feature of normal development and tissue homeostasis. Without cell migration, embryos would not develop, wounds would never heal, and the immune system could n...
The Gordon Research Conference (GRC) on the Cell Biology of Megakaryocytes and Platelets is the premier international scientific meeting focused on the biology of the megakaryocyte lineage, from HSCs ...
Germline cells play a unique and pivotal role as the carriers of genetic information from one generation to the next. Intense interest has centred on their origins, how their properties and behaviour ...
Proliferation of cells represents one of the most fundamental biological processes. The core cell cycle machinery that drives cell proliferation has been conserved from yeast to humans. Proper spatial...
We propose a novel multi-photon evanescent wave (MPEW) excitation modality for upconverting nanoparticles (UCNPs) based microscopy. Experimental results show this new imaging method for UCNPs is nonsc...
When cells die, whether through apoptosis or necrosis, the DNA and other molecules found in those cells don’t just disappear. They wind up in the blood stream, where degraded bits and pieces can be ex...
Background: Alterations in p53 and p27KIP1 have been documented as important events in the carcinogenesis of various cancers, but their prognostic role in oral squamous cell carcinoma (OSCC) remains c...
Immune response enables the body to resist foreign invasions. The Inflammatory response is an important aspect in the immune response which is articulated by elements such as cytokines, APC, T-cell an...
Introduction: Matrix metalloproteinases (MMPs) are known for their role in extracellular matrix remodeling, but their role in regulating intracellular immune cell function is unknown. We reported that...
Stem cell factor (SCF) mediated c-Kit signaling, and downstream activation of Phosphatidylinositol-3 Kinase (PI-3K) is critical for multiple biological effects mediated by mast cells. Mast cells expre...
Neurofibromatosis type 1 is a genetic disease that results from either heritable or spontaneous autosomal dominant mutations in the NF1 gene, which encodes a protein serving, at least in part, to acce...
The complex pathogenesis of emphysema involves disappearance of alveolar structures, in part attributed to alveolar cell apoptosis. The mechanism by which cigarette smoke (CS) induces alveolar cell ap...

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