搜索结果: 61-69 共查到“药理学 血压”相关记录69条 . 查询时间(0.234 秒)
丁基苯酞对脑卒中型自发性高血压大鼠寿命及卒中后神经症状的影响
丁基苯酞 卒中型自发性高血压大鼠 脑卒中 尼莫地平
2010/2/23
本实验研究了dl-3-正丁基苯酞(NBP)在高盐负荷下,对卒中型自发性高血压大鼠(SHRsp)寿命及卒中后存活时间和神经症状的影响。实验证明NBP能延迟脑卒中发生;能延长脑卒中发作后的存活时间和减轻神经症状。NBP对SHRsp大鼠的血压和心率无明显影响。
粉防己碱可显著降低DOCA盐性高血压心肌肥厚大鼠的血压,左室湿重;在工作心脏研究中发现其改善肥厚心室的收缩(AP,LVSP,+dp/dtmax)舒张(一dp/dtmax,LVEDP,T值)性能,尤以舒张性能改善明显,并恢复泵功能(CO)和冠脉流量(CF);在左室压力容积关系法研究显示有改善肥厚心室左室顺应性和左室僵硬度的作用。提示:Tet有逆转心肌肥厚和改善肥厚心肌舒张收缩功能,左室顺应性和心肌劲...
间硝地平对高血压心肌肥厚老龄鼠肾和肺细胞膜二氢吡啶受体的影响
间硝地平 高血压 受体 二氢吡啶
2010/2/25
Effects of m-nifedipine(m-Nif)on the affinity and density of dihydropyridine(DHP)binding sites in the cell membranes of kidney and lung were investigated using the LVH(leftventricular hypertrophy )ind...
动脉血压改变对大鼠下丘脑后部GABA释放的影响
下丘脑后部 γ-氨基丁酸 动脉血压 推～挽灌流
2010/2/26
用推～挽灌流技术,定位灌流大鼠下丘脑后部,同时iv给予去氧肾上腺素(15μg·kg·min-1)和静脉输血(3ml/100g,wt)引起血压升高时,下丘脑后部γ-氨基丁酸(GABA)的释放率增加,而iv给予硝普钠、氯化四氯吲哚铵和控制性失血导致血压下降时,GABA的释放率减少。进一步证明下丘脑GABA能神经系统参与外周动脉血压的调节,且有降压作用。
苯氧烷胺类化合物的合成及其抗高血压活性
α-受体亲和力 降压活性 苯氧烷胺
2010/1/29
Nine new compounds were synthesized and tested for their α-adrenoceptor affinity and antihypertensive activity together with 5 other previously reported compounds(1). Compounds Ⅰ, Ⅱa, Ⅱb and Ⅲa showed...
碘化二甲基木防己碱对清醒及急性肾型高血压大鼠的降压作用
碘化二甲基木防己碱 急性肾型高血压大鼠 降压作用
2010/3/22
In acute renal hypertensive rats, the blood pressure could be reduced from 148.8±7.9 mmHg to 123.6±9.3 mmHg by intravenous injection of dimethyl trilobine iodide (DTI) at the dosage of 0.5 mg/kg. The ...
Captopril is a novel orally active inhibitor of angiotensin Ⅰ coverting enzyme and antihypertensive agent. In the present experiment we have found thati captopril has different effects on blood pressu...
长效硝酸异山梨醇酯片的体外释放和麻醉猫血压变化的关系
长效硝酸异山梨醇酯片 体外释放 麻醉 猫 血压变化
2010/3/25
The in vitro release of isosorbide dinitrate from a sustained-release tablet was determined by using 0.1N HCl, a simulated gastric fluid for the first 3 hr and phosphate buffer solution pH 7.2～7.4, an...