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An effect of CO2 on the maximum safe direct decompression to 1 bar from oxygen-nitrogen saturation
saturation nitrogen human carbon dioxide
2009/7/14
An investigation into the maximum safe decompression step from oxygen nitrogen saturation to 1 bar was carried out with and without the presence of 0.02 bar carbon dioxide. The series, Islander 1, inv...
Effect of pressure on oxidative metabolism of drugs by mouse hepatic microsomes
animal mice oxidative metabolism hepatic microsomes delta-9-tetrahydrocannabinol Cannabis drug
2009/7/14
The metabolism of antipyrene and delta-9-tetrahydrocannabinol (delta-9-THC) was studied in vitro with mouse liver supernatant and 105,000 g microsomes at 450 atm pressure. No significant change in rat...
Effect of barbituric acid on the high pressure nervous syndrome in the rat
neurological rat animal high pressure nervous syndrome barbituric acid
2009/7/14
Male Sprague-Dawley rats were compressed in helium-oxygen mixture at a rate of 3 bar/min. Compression ended once the first convulsion was seen. Saline or barbituric acid at 1 or 2percent were infused ...
A method for production of N2 microbubbles in platelet-rich plasma in an aggregometer-like apparatus,and effect on the platelet density in vitro
decompression human platelet
2009/7/14
The mechanisms involved in the interactions between microgasbubbles and platelets are not clear. The platelet aggregatory response to agonist-induced, receptor-mediated stimuli has been studied extens...
Effect of 2-aminophosphonoheptanoic acid on the EEG of rats exposed to high pressure
neurological rat animal
2009/7/14
Excitatory amino acid neurotransmission may be involved in the tremor component of the high pressure neurological syndrome (HPNS). 2-Amino-7-phosphonoheptanoic acid (2-APH) is a novel antagonist of ex...
Anesthetic effect and distribution of infused pentobarbital in the rat at 71 ATA
drug anesthesia pentobarbital animal rat
2009/7/14
The anesthetic dose requirement and distribution of 14C-labeled pentobarbital were studied in rats at 1 ATA air and at 71 ATA He-O2. Pentobarbital was infused intravenously at a rate of 5 mg X kg-1 X ...
The effect of high pressure on the kinetics of monoamine transmitters in the rat brain
drug hyperbaric serotonin noradrenaline dopamine animal rat monoamine transmitter
2009/7/14
The effects of 71 ATA pressure on the turnover of serotonin (5-HT), noradrenaline (NA), and dopamine (DA) were studied. High pressure increased the concentration of the 5-HT metabolite 5-hydroxyindole...
Evaluation of noise within the MK 12 SSDS helmet and its effect on divers' hearing
human diver equipment MK 12 SSDS helmet Audiometry Hearing Noise
2009/7/14
The noise inside the U.S. Navy MK 12 SSDS helmet was measured and its effect on the hearing of divers assessed. Seven male divers completed 20 dives while breathing air at simulated depths ranging fro...
Effect of hydrostatic pressure on plasma concentrations of norepinephrine during cold water immersion
human plasma norepinephrine thermal immersion
2009/7/14
Head-out immersion of humans in cold water concurrently stimulates low-pressure receptors and cutaneous cold receptors. In theory, the low-pressure receptors inhibit sympathetic nerve activity to the ...
Effect of 5 bar oxygen on cardiac output and organ blood flow in conscious rats
HBO equipment hyperbaric cardiac output animal rat
2009/7/14
The distribution of cardiac output (CO) was studied in conscious rats during hyperbaric oxygen (HBO) exposure to 5 bar for 60 min. Heart rate (HR) and arterial blood pressure (ABP) were continuously r...
Effect of benzazole-related centrally acting muscle relaxants on HPNS
benzazole high pressure nervous syndrome animal mice
2009/7/14
A series of benzazole-related, centrally acting muscle relaxants, comprising benzimidazole, chlorzoxazone, and zoxazolamine, were found to give substantial protection against the tremors and convulsio...
Effect of wearing gloves on the thermal balance of Korean women wet-suit divers in cold water
cold wet suit immersion neoprene gloves thermal protection
2009/7/10
Effect of wearing neoprene gloves on the thermal exchanges of wet-suited divers was studied in 8 Korean diving women. Subjects, clad with 5-6-mm-thick neoprene wet suits (jacket, pants, and boots) eit...
Effect of peripheral temperature on the formation of venous gas bubbles
cold decompression bubble formation peripheral temperature extremities
2009/7/9
Temperature of the tissue affects the many components involved in the formation of tissue gas phase formation: diffusion, perfusion, and inert gas solubility. Since the effects of perfusion and inert ...
Effect of He-O2,O2,and N2O-O2 breathing on injected bubbles in spinal white matter
oxygen heliox decompression animal rat nitrous oxide spinal white matter
2009/7/8
Injected air bubbles in spinal white matter in the rat were studied at 1 bar after decompression from an exposure to air at 3.1 bar (absolute) for 4 h. During air breathing all injected bubbles grew f...
Effect of inspiratory-phase negative pressure breathing on urine flow in man
negative pressure urine
2009/7/8
We investigated the effect of negative pressure breathing during the inspiratory phase only (intermittent NPB) in 9 healthy male subjects who were in a sitting position and had no food or fluid intake...