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Determining the exact configuration of proteins and other complex biological molecules is an important step toward understanding their functions, including how they bind with receptors in the body. Bu...
Atomic structure of a single large biomolecule from diffraction patterns of random orientations
X-ray free electron lasers Single particle x-ray diffraction Orientation Structure reconstruction
2012/4/20
The short and intense pulses of the new X-ray free electron lasers, now operational or under construction, may make possible diffraction experiments on single molecule-sized objects with high resoluti...