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Characterization of the sperm factor responsible for initiating [Ca2+]i oscillations during fertilization in mammalian eggs
Biological sciences Sperm factor Oscillations Fertilization Mammalian eggs
2015/1/28
During fertilization the sperm activates the mammalian egg by eliciting [Ca2+]i oscillations. However, how the sperm triggers [Ca2+]i oscillations in mammalian eggs remains unknown. To test the possib...
The role of inositol 1,4,5 -trisphosphate receptor type-1 in regulation of intracellular calcium oscillations in mouse eggs
Calcium mammals fertilization eggs activation embryonic development cell cycle inositol receptor
2014/12/11
Calcium ([Ca2+]i) oscillations, a hallmark of mammalian fertilization, are essential to induce egg activation and embryonic development. As the zygotes transition through the cell cycle, these [Ca 2+]...
Switching between oscillations and homeostasis in competing negative and positive feedback motifs
negative feedback positive feedback oscillation noise circadian rhythm
2012/5/2
We analyze a class of network motifs in which a short, two-node positive feed- back motif is inserted in a three-node negative feedback loop. We demonstrate that such networks can undergo a bifurcatio...
Infinite-Period Phase Transition versus Nucleation in a Stochastic Model of Collective Oscillations
Infinite-Period Phase Transition Collective Oscillations
2011/9/2
A lattice model of three-state stochastic phase-coupled oscillators has been shown by Wood et al. [Phys. Rev. Lett. 96, 145701 (2006)] to exhibit a phase transition at a critical value of the coupling...