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TFAM作为自噬受体介导胞质中mtDNA的清除进而限制炎症反应(图)
炎症 线粒体 蛋白复合物
2024/8/26
2024年5月23日,广州医科大学冯杜团队在Nature Cell Biology在线发表论文,报道了TFAM作为自噬受体介导胞质中mtDNA的清除,进而限制炎症反应
【目的】探讨甘肃截形叶螨Tetranychus truncatus种群遗传多样性、遗传分化及种群系统发育关系。【方法】本研究以2016年6-9月采自甘肃省8个不同生境的34个截形叶螨种群的518头螨样品进行mtDNA COI基因PCR扩增、测序,并利用MEGA7.0和Dna SP5.0等软件分析截形叶螨不同种群的mtDNA COI基因序列变异和遗传分化情况。【结果】在34个截形叶螨地理种群中共获得...
mtDNA稀有变异或是精神分裂症一种病因
mtDNA稀有变异 精神分裂症
2016/8/4
近日,中国科学院昆明动物研究所研究员姚永刚、博士生毕蕊与中南大学湘雅二医院陈晓岗团队合作,对11个展现出母系遗传特征的精神分裂症家系进行了研究,通过测定各家系中先证者的mtDNA全基因组序列发现,mtDNA稀有致病变异可能是精神分裂症发病的一种病因,但其低频异质性很可能与精神分裂症不相关。相关结果近期分别发表于《精神分裂症的研究》 和《分子神经生物学》期刊。
Haplogroup Classification of Korean Cattle Breeds Based on Sequence Variations of mtDNA Control Region
Haplogroup mtDNA Control Region Korean Cattle Breed Phylogenetic Tree
2016/5/20
Many studies have reported the frequency and distribution of haplogroups among various cattle breeds for verification of their origins and genetic diversity. In this study, 318 complete sequences of t...
Genetic Diversity and Phylogenetic Analysis of South-East Asian Duck Populations Based on the mtDNA D-loop Sequences
Duck Populations D-loop Region Haplotype Mitochondrial DNA Phylogeny
2016/12/28
The maternally inherited mitochondrial DNA (mtDNA) D–loop region is widely used for exploring genetic relationships and for investigating the origin of various animal species. Currently, domestic duck...
贵州东北部黑叶猴种群mtDNA D-loop序列多态性
黑叶猴 线粒体控制区 单倍型 遗传多样性
2016/7/18
贵州东北部作为黑叶猴在中国的主要分布区之一,黑叶猴的数量在近 30 年急剧下降,栖息地破碎化严重,保护形势不容乐观。深入了解黑叶猴在贵州东北部地区地理种群的分子变异及遗传水平现状,可以为黑叶猴保护提供重要的依据。本文以黑叶猴的粪便、毛发为实验材料,利用线粒体DNA分子标记,对采自贵州东北部地区黑叶猴野生种群79个粪便样品和黔灵公园笼养种群22个粪便样品、5份毛发样品的线粒体控制区(mtDNA D-...
We reexamined two mysterious beaked whale specimens stranded in Changle city of Fujian Province for species identification based on mtDNA sequences and morphological characters.By using DNA sequence s...
Effects of α-lipoic Acid on mtDNA Damage after Isolated Muscle Contractions
ISOLATED EXERCISE >-LIPOIC ACID PROPHYLAXIS MITOCHONDRIAL DNA DAMAGE LIPID PEROXIDATION
2017/7/17
ntroduction: Although pharmacological antioxidants have previously been investigated for a prophylactic effect against exercise oxidative stress, it is not known if α-lipoic acid supplementation can p...
Genetic Diversity of mtDNA D-loop Polymorphisms in Laotian Native Fowl Populations
Native Fowl Genetic Variability mtDNA Maternal Origin
2016/5/16
Here, we studied the genetic diversity of native fowls in Laos by analyzing a mitochondrial DNA (mtDNA) sequence polymorphism. A 546-bp fragment of the mtDNA D-loop region was sequenced in 129 chicken...
mtDNA Diversity and Phylogenetic State of Korean Cattle Breed, Chikso
Phylogenetic Analysis Chikso Haplotype mtDNA Cytochrome
2016/5/11
In order to analyze the genetic diversity and phylogenetic status of the Korean Chikso breed, we determined sequences of mtDNA cytochrome b (cyt b) gene and performed phylogenetic analysis using 239 i...
Phylogenetic Analysis of a Privately-owned Korean Native Chicken Population Using mtDNA D-loop Variations
D-loop Variation Haplotype Korean Native Chicken mtDNA
2016/5/11
The use of Korean native chicken is increasing, and the discovery of new genetic resources is very important from both economic and genetic conservation points of view. In this study, mtDNA D-loop seq...
Effect of Population Reduction on mtDNA Diversity and Demographic History of Korean Cattle Populations
Cattle Mitochondrial DNA Genetic Diversity Population Expansion
2016/5/10
The population sizes of three Korean indigenous cattle populations have been drastically reduced over the past decades. In this study, we examined the extent to which reduction in populations influenc...
Genetic Diversity of mtDNA D-loop and Maternal Origin of Three Chinese Native Horse Breeds
Chinese Western Native Horses Mitochondrial DNA D-loop Genetic Diversity Maternal Origin
2016/5/10
In order to protect the genetic resource of native horse breeds, the genetic diversity of mitochondrial DNA (mtDNA) D-loop of three native horse breeds in western China were investigated. Forty-three ...
稀有白甲鱼西江种群mtDNA D环区的结构及遗传多样性
稀有白甲鱼 mtDNA D环 遗传多样性 西江
2012/3/19
采用PCR扩增和DNA直接测序技术,测定分析了采自珠江水系西江的30尾稀有白甲鱼(Onychostoma rara)mtDNA D环约467 bp的序列。结果显示,该序列的长度为467~470 bp,共计发现了16个变异位点,占分析总位点数的3.40%,其碱基组成A+T的平均含量(67.6%)高于C+T(32.3%)。稀有白甲鱼西江种群mtDNA D环区在结构上可分为终止序列区、中央保守区和保守序...
Discrimination of Korean Native Chicken Populations Using SNPs from mtDNA and MHC Polymorphisms
mtDNA LEI0258 Marker Discrimination Korean Native Chicken
2016/5/9
Korean native chickens are a very valuable chicken population in Korea and their prices are higher than that of commercial broilers. In order to discriminate two commercial Korean native chicken popul...