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A fused lasso latent feature model for analyzing multi-sample aCGH data
Cancer DNA copy number False discovery rate Mutation
2015/8/21
Array-based comparative genomic hybridization (aCGH) enables the measurement of DNA copy number across thousands of locations in a genome. The main goals of analyzing aCGH data are to identify the reg...
Numerical analysis of a reinforcement learning model with the dynamic aspiration level in the iterated Prisoner's Dilemma
Numerical analysis reinforcement learning model
2011/1/5
Humans and other animals can adapt their social behavior in response to environmental cues including the feedback obtained through experience. Nevertheless, the effects of the experience-based learnin...
An algebraic analysis of the two state Markov model on tripod trees
algebraic analysis Markov model tripod trees
2011/1/5
Methods of phylogenetic inference use more and more complex models to generate trees from data. However, even simple models and their implications are not fully understood. Here, we investigate the tw...
Sensitivity analysis of a computational model of the IKK-NF-κB-IκBα-A20 signal transduction network
Sensitivity analysis computational model IKK-NF-κB-IκBα-A20 signal transduction
2010/11/15
The NF-{\kappa}B signaling network plays an important role in many different compartments of the immune system during immune activation. Using a computational model of the NF-{\kappa}B signaling netw...
Biological cells with all of their surface structure and complex interior stripped away are essentially vesicles - membranes composed of lipid bilayers which form closed sacs. Vesicles are thought to ...