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Changes in leukocyte counts, lymphocyte subpopulations and the mRNA expression of selected cytokines in the peripheral blood of dogs with atopic dermatitis
chronic inflammation B-lymphocytes double-positive lymphocytes stress
2015/11/26
Canine atopic dermatitis (CAD) is a chronic allergic disease characterised by genetic predisposition.
The exact pathogenesis of the disease is still not fully understood. Blood parameters, lymphocyt...
Maternal thyroid hormone regulates gene expression in the fetal rat brain
Clinical thyroid hormone the fetus gene
2014/12/11
Recent clinical evidence indicates that thyroid hormone plays an essential role in fetal brain development. However, the mechanism by which thyroid hormone affects development has been largely unexplo...
EGFR expression and activation in bovine cumulus cells and EGFR intramolecular regulation through interactions between tyrosines
Epidermal growth factor receptor the process of cell the cell cycle cell migration cell metabolism cell proliferation oocytes and embryo development activation of cumulus cells
2014/12/11
The epidermal growth factor receptor (EGFR) plays important roles in the control of many fundamental cellular processes including cell cycle, cell migration, cell metabolism and survival, cell prolife...
Modulation of Nhlh2 expression by energy availability leads to downstream effects on body weight regulation
The hypothalamus transcription factors nerve energy hormone neurons arcuate nucleus neurons
2014/12/11
Mice with a deletion of the hypothalamic basic helix-loop-helix transcription factor Nhlh2 (N2KO) display adult onset obesity, implicating Nhlh2 in the neuronal circuits regulating energy availability...
Mapping Dynamic Histone Acetylation Patterns to Gene Expression in Nanog-depleted Murine Embryonic Stem Cells
Mapping Dynamic Histone Acetylation Patterns Gene Expression in Nanog-depleted Murine Embryonic Stem Cells
2010/11/15
Embryonic stem cells (ESC) have the potential to self-renew indefinitely and to differentiate into any of the three germ layers. The molecular mechanisms for self-renewal, maintenance of pluripotency ...
STAT PROTEIN REGULATION OF FOXP3 EXPRESSION AND INFLAMMATORY CYTOKINE PRODUCTION IN T HELPER CELL SUBSETS
Stat proteins Stat4 cytokines inflammation Foxp3
2015/5/21
ThedifferentiationofnaïveCD4+TcellsintosubsetsofThelpercells(Th)isan
essentialprocessthatimpactshostdefenseandthepathogenesisofimmunemediated
diseases.Signaltransducersandactivatorsoftranscript...